日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

New Dual Pan-PI3K/mTOR Inhibitor: Design, Synthesis, Cytotoxic Action, Permeation, Metabolic Stability, and In Silico Protein-Ligand Interaction

新型双重泛PI3K/mTOR抑制剂：设计、合成、细胞毒性作用、渗透性、代谢稳定性及计算机模拟蛋白-配体相互作用

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c10162
Aparecida E Silva, Cristiane; Pillpe-Meza, Raysa Magali; Gouveia, Wesley Leandro; da Silva Trindade, Joana D'Arc; Barbosa, Gisele; Vieira, Amanda Marques Seixas; Tolomeu, Heber Victor; Pereira, Rayane França; Santos, Carlos Antônio do Nascimento; Freire-de-Lima, Leonardo; Lima, Lidia Moreira
细胞生物学
mTOR
毒理研究
代谢
发表日期：2026
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Hit-to-Lead Studies of Pyrazinylpiperazines against Visceral Leishmaniasis: Pharmacokinetic Profile and In Vivo Efficacy of Potent Compounds against Leishmania infantum.

吡嗪基哌嗪类化合物对内脏利什曼病的先导化合物研究：强效化合物对婴儿利什曼原虫的药代动力学特征和体内疗效

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00318
Jacques Dit Lapierre Thibault Joseph William, Gabriela Faleiro de Moura Lodi Cruz Mariza, Barbosa Gisele, Costa Analu R, Chávez-Fumagalli Miguel Angel, Froes Thamires Quadros, Ramos Priscila Zonzini, Macruz Paula Derksen, Carolyne Souza Trindade Thalita, Pilau Eduardo Jorge, Sampaio Tavares Veras Patricia, Nonato Maria Cristina, Massirer Katlin B, Ferreira Leonardo L G, Andricopulo Adriano D, Lima Lídia Moreira, Murta Silvane Maria Fonseca, Rezende Júnior Celso de Oliveira
其它
发表日期：2025
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Investigation on LASSBio-1971 and LASSBio-1974 Cellular Cytotoxic Mechanism and Their Comparative DMPK Profile

LASSBio-1971 和 LASSBio-1974 细胞毒性机制及其 DMPK 特征比较研究

期刊:Archiv der Pharmazie
影响因子:3.6
doi:10.1002/ardp.70151
de Moraes Junior, Manoel Oliveira; Barbosa, Gisele; da Costa, Caroline Marques Xavier; Pillpe-Meza, Raysa Magali; de Gouveia, Wesley Leandro; do Amaral, Daniel Nascimento; Gelves, Luis Gabriel Valdivieso; Laufer, Stefan; Lima, Lídia Moreira
细胞生物学
毒理研究
DMPK
发表日期：2025
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Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease-Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

从富含蛋白酶的水果中分离的镰刀菌和土曲霉的生物活性代谢物研究：抗真菌、抗锥虫和酶抑制活性

期刊:Chemistry & Biodiversity
影响因子:2.5
doi:10.1002/cbdv.202500673
de Oliveira Almeida, Gabriela; Mazucato, Vitor de Souza; Tonani, Ludmilla; von Zeska Kress, Marcia Regina; Barbosa, Gisele; Krogh, Renata; Andricopulo, Adriano Defini; Gomes Ferreira, Leonardo Luiz; Vieira, Paulo Cezar
微生物学
代谢
发表日期：2025
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Co-cultivation and Medium Optimization: A Strategy for Discovering Fungal-derived Protease Inhibitors

共培养和培养基优化：发现真菌来源蛋白酶抑制剂的策略

期刊:Chemistry & Biodiversity
影响因子:2.5
doi:10.1002/cbdv.202501135
Mazucato, Vitor de Souza; Tonani, Ludmilla; von Zeska Kress, Marcia Regina; Andricopulo, Adriano Defini; Barbosa, Gisele; Krogh, Renata; Gomes Ferreira, Leonardo Luiz; Vieira, Paulo Cezar
微生物学
发表日期：2025
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Comparable Ventilatory Inefficiency at Maximal and Submaximal Performance in COPD vs. CHF subjects: An Innovative Approach

慢性阻塞性肺疾病（COPD）患者与充血性心力衰竭（CHF）患者在最大和次最大运动强度下通气效率相当：一种创新方法

期刊:
影响因子:
doi:10.36660/abc.20230578
de Campos, Gerson Gatass Orro; Goelzer, Leandro Steinhorst; Augusto, Tiago Rodrigues de Lemos; Barbosa, Gisele Walter; Chiappa, Gaspar R; van Iterson, Erik H; Muller, Paulo T
COPD
心力衰竭
心血管
慢性阻塞性肺疾病
发表日期：2024
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Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs

利用表型方法在LASSBio-1586同源物中发现微管蛋白和EGFR的潜在双重抑制剂

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph15080913
Barbosa, Gisele; Gelves, Luis Gabriel Valdivieso; Costa, Caroline Marques Xavier; Franco, Lucas Silva; Lima, João Alberto Lins de; Aparecida-Silva, Cristiane; Teixeira, John Douglas; Mermelstein, Claudia Dos Santos; Barreiro, Eliezer J; Lima, Lidia Moreira
EGFR
EGF
发表日期：2022
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PKCζ-Mitogen-Activated Protein Kinase Signaling Mediates Crotalphine-Induced Antinociception

PKCζ-丝裂原活化蛋白激酶信号介导克罗他林诱导的镇痛作用

期刊:Toxins
影响因子:
doi:10.3390/toxins13120912
Bárbara G de Freitas, Natália G Hösch, Leandro M Pereira, Tereza C Barbosa, Gisele Picolo, Yara Cury, Vanessa O Zambelli
信号转导
发表日期：2021
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Cardiopulmonary and Muscular Interactions: Potential Implications for Exercise (In)tolerance in Symptomatic Smokers Without Chronic Obstructive Pulmonary Disease

心肺和肌肉相互作用：对无慢性阻塞性肺疾病症状吸烟者运动（不）耐受性的潜在影响

期刊:Frontiers in Physiology
影响因子:3.4
doi:10.3389/fphys.2019.00859
Muller, Paulo de Tarso; Barbosa, Gisele Walter; O'Donnell, Denis E; Neder, J Alberto
慢性阻塞性肺疾病
发表日期：2019
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Shoulder injuries in soccer goalkeepers: review and development of a FIFA 11+ shoulder injury prevention program

足球守门员肩部损伤：FIFA 11+肩部损伤预防方案的回顾与发展

期刊:Open Access Journal of Sports Medicine
影响因子:1.6
doi:10.2147/OAJSM.S97917
Ejnisman, Benno; Barbosa, Gisele; Andreoli, Carlos V; de Castro Pochini, A; Lobo, Thiago; Zogaib, Rodrigo; Cohen, Moises; Bizzini, Mario; Dvorak, Jiri
发表日期：2016
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