Off-the-shelf Vδ1 gamma delta T cells engineered with glypican-3 (GPC-3)-specific chimeric antigen receptor (CAR) and soluble IL-15 display robust antitumor efficacy against hepatocellular carcinoma
用磷脂酰肌醇蛋白聚糖-3 (GPC-3) 特异性嵌合抗原受体 (CAR) 和可溶性 IL-15 改造的现成 Vδ1 伽马德尔塔 T 细胞对肝细胞癌表现出强大的抗肿瘤功效
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2021-003441
Amani Makkouk, Xue Cher Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman
