日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1

ATOR-1017 (evunzekibart) 是一种 Fc-γ 受体条件性 4-1BB 激动剂,旨在实现最佳安全性和有效性,与抗 PD-1 联合使用可激活耗竭的 T 细胞

Karin Enell Smith #, Sara Fritzell #, Anneli Nilsson, Karin Barchan, Anna Rosén, Lena Schultz, Laura Varas, Anna Säll, Nadia Rose, Maria Håkansson, Laura von Schantz, Peter Ellmark

The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation

CTLA-4 x OX40 双特异性抗体 ATOR-1015 通过肿瘤导向免疫激活诱导抗肿瘤作用

Anne Månsson Kvarnhammar, Niina Veitonmäki, Karin Hägerbrand, Anna Dahlman, Karin Enell Smith, Sara Fritzell, Laura von Schantz, Mia Thagesson, Doreen Werchau, Kristine Smedenfors, Maria Johansson, Anna Rosén, Ida Åberg, Magnus Winnerstam, Eva Nyblom, Karin Barchan, Christina Furebring, Per Norlén, 

Two subsites in the binding domain of the acetylcholine receptor: an aromatic subsite and a proline subsite

乙酰胆碱受体结合域包含两个亚位点:芳香族亚位点和脯氨酸亚位点。

Kachalsky, S G; Jensen, B S; Barchan, D; Fuchs, S

How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor

獴如何对抗蛇:獴乙酰胆碱受体的结合位点

Barchan, D; Kachalsky, S; Neumann, D; Vogel, Z; Ovadia, M; Kochva, E; Fuchs, S

Snake acetylcholine receptor: cloning of the domain containing the four extracellular cysteines of the alpha subunit

蛇乙酰胆碱受体:α亚基包含四个胞外半胱氨酸的结构域的克隆

Neumann, D; Barchan, D; Horowitz, M; Kochva, E; Fuchs, S

Mapping of the alpha-bungarotoxin binding site within the alpha subunit of the acetylcholine receptor

乙酰胆碱受体α亚基内α-银环蛇毒素结合位点的定位

Neumann, D; Barchan, D; Safran, A; Gershoni, J M; Fuchs, S

Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor alpha subunit

分析乙酰胆碱受体α亚基合成十二肽185-196与配体的结合情况

Neumann, D; Barchan, D; Fridkin, M; Fuchs, S