日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic Insights of a p53-Targeting Small Molecule

p53靶向小分子的机制研究

Ferreira, Ricardo J F; Barcherini, Valentina; Roma-Rodrigues, Catarina; Sikorová, Miriama; Saraiva, Lucília; Leandro, Ana P; Baptista, Pedro V; Fernandes, Alexandra R; Antunes, Alexandra M M; Santos, Maria M M

Metabolism-Guided Optimization of Tryptophanol-Derived Isoindolinone p53 Activators

色氨酸衍生的异吲哚酮 p53 激活剂的代谢引导优化

Valentina Barcherini, Joana B Loureiro, Ana Sena, Catarina Madeira, Paula Leandro, Lucília Saraiva, Alexandra M M Antunes, Maria M M Santos

Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance

针对 p53 治疗黑色素瘤:对抗肿瘤增殖、扩散和治疗耐药性

Joana B Loureiro, Liliana Raimundo, Juliana Calheiros, Carla Carvalho, Valentina Barcherini, Nuno R Lima, Célia Gomes, Maria Inês Almeida, Marco G Alves, José Luís Costa, Maria M M Santos, Lucília Saraiva

SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner

SLMP53-1 通过 P53 依赖的方式调节葡萄糖代谢和血管生成来抑制肿瘤细胞生长

Helena Ramos, Juliana Calheiros, Joana Almeida, Valentina Barcherini, Sónia Santos, Alexandra T P Carvalho, Maria M M Santos, Lucília Saraiva

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma

SLMP53-2 通过 Hsp70 恢复突变型 p53 的野生型功能:在肝细胞癌中具有良好的活性

Sara Gomes, Bartolomeo Bosco, Joana B Loureiro, Helena Ramos, Liliana Raimundo, Joana Soares, Nair Nazareth, Valentina Barcherini, Lucília Domingues, Carla Oliveira, Alessandra Bisio, Silvano Piazza, Matthias R Bauer, João P Brás, Maria Inês Almeida, Célia Gomes, Flávio Reis, Alan R Fersht, Alberto

Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence

结肠镜息肉切除术在标准临床实践中降低结直肠癌发病率的疗效

Citarda, F; Tomaselli, G; Capocaccia, R; Barcherini, S; Crespi, M