Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library
利用自分泌细胞筛选法,从组合抗体库中筛选出全人源TrkB激动剂抗体
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1806660115
Merkouris, Spyros; Barde, Yves-Alain; Binley, Kate E; Allen, Nicholas D; Stepanov, Alexey V; Wu, Nicholas C; Grande, Geramie; Lin, Chih-Wei; Li, Meng; Nan, Xinsheng; Chacon-Fernandez, Pedro; DiStefano, Peter S; Lindsay, Ronald M; Lerner, Richard A; Xie, Jia