日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design

通过工程改造SIRPα构象可塑性,揭示一个适合基于结构的药物设计的隐蔽口袋。

Storder, M; Barelier, S; Cordier, F; Yacoub, T; Ilari, L; Barral, K; Mahmoodi, S; Saez-Ayala, M; Combes, S; Betzi, S; Derviaux, C; Ulliana, A; Torres, F; Rubin, J; Roche, P; Morelli, X; Garcin, E D; Miller, T W

ChemoDOTS: a web server to design chemistry-driven focused libraries

ChemoDOTS:一个用于设计化学驱动型聚焦库的Web服务器

Hoffer, Laurent; Charifi-Hoareau, Guillaume; Barelier, Sarah; Betzi, Stéphane; Miller, Thomas; Morelli, Xavier; Roche, Philippe

Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases

腺苷类似物的结构引导优化作为冠状病毒 nsp14 N7-甲基转移酶的选择性和有效抑制剂

Marcel Hausdorff, Adrien Delpal, Sarah Barelier, Laura Nicollet, Bruno Canard, Franck Touret, Agathe Colmant, Bruno Coutard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart

Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis

粪肠球菌主要N-乙酰氨基葡萄糖苷酶AtlA识别底物和隔膜裂解的分子基础

Roig-Zamboni, Véronique; Barelier, Sarah; Dixon, Robert; Galley, Nicola F; Ghanem, Amani; Nguyen, Quoc Phong; Cahuzac, Héloize; Salamaga, Bartłomiej; Davis, Peter J; Bourne, Yves; Mesnage, Stéphane; Vincent, Florence

Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.

Vif 抗 APOBEC3 活性进化过程中谱系特异性病毒劫持非经典 E3Â 泛素连接酶辅因子

Kane Joshua R, Stanley David J, Hultquist Judd F, Johnson Jeffrey R, Mietrach Nicole, Binning Jennifer M, Jónsson Stefán R, Barelier Sarah, Newton Billy W, Johnson Tasha L, Franks-Skiba Kathleen E, Li Ming, Brown William L, Gunnarsson Hörður I, Adalbjornsdóttir Adalbjorg, Fraser James S, Harris Reuben S, Andrésdóttir Valgerður, Gross John D, Krogan Nevan J

The Recognition of Identical Ligands by Unrelated Proteins

无关蛋白质对相同配体的识别

Barelier, Sarah; Sterling, Teague; O'Meara, Matthew J; Shoichet, Brian K

Substrate deconstruction and the nonadditivity of enzyme recognition

底物解构和酶识别的非加和性

Barelier, Sarah; Cummings, Jennifer A; Rauwerdink, Alissa M; Hitchcock, Daniel S; Farelli, Jeremiah D; Almo, Steven C; Raushel, Frank M; Allen, Karen N; Shoichet, Brian K

Increasing chemical space coverage by combining empirical and computational fragment screens

通过结合经验和计算碎片筛选来增加化学空间覆盖率

Sarah Barelier, Oliv Eidam, Inbar Fish, Johan Hollander, Francis Figaroa, Ruta Nachane, John J Irwin, Brian K Shoichet, Gregg Siegal

Roles for ordered and bulk solvent in ligand recognition and docking in two related cavities

有序溶剂和本体溶剂在配体识别和对接中两个相关空腔的作用

Barelier, Sarah; Boyce, Sarah E; Fish, Inbar; Fischer, Marcus; Goodin, David B; Shoichet, Brian K

Discovery of fragment molecules that bind the human peroxiredoxin 5 active site

发现能与人过氧化物酶5活性位点结合的片段分子

Barelier, Sarah; Linard, Dominique; Pons, Julien; Clippe, André; Knoops, Bernard; Lancelin, Jean-Marc; Krimm, Isabelle