Valproic acid improves the efficacy of oxaliplatin/fluoropyrimidine-based chemotherapy by targeting cancer stem cell via β-Catenin modulation in colorectal cancer.
丙戊酸通过调节β-catenin靶向结直肠癌中的癌症干细胞，从而提高奥沙利铂/氟尿嘧啶类化疗的疗效
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07902-8
Roca Maria Serena, Lombardi Rita, Testa Cristina, Iannelli Federica, Grumetti Laura, Moccia Tania, Barile Veronica, Addi Laura, Memoli Domenico, Leone Alessandra, Di Franco Simone, Stassi Giorgio, Avallone Antonio, Bruzzese Francesca, Pucci Biagio, Budillon Alfredo, Di Gennaro Elena
发育与干细胞
细胞生物学
肠癌
Wnt/β-Catenin
肿瘤免疫
