日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

人诱导多能干细胞来源的小胶质细胞移植到新生小鼠脑后,会呈现出类似原代小胶质细胞的状态。

Svoboda, Devon S; Barrasa, M Inmaculada; Shu, Jian; Rietjens, Rosalie; Zhang, Shupei; Mitalipova, Maya; Berube, Peter; Fu, Dongdong; Shultz, Leonard D; Bell, George W; Jaenisch, Rudolf

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression.

α-突触核蛋白远端增强子中的帕金森病相关风险变异体调节靶基因表达

Soldner Frank, Stelzer Yonatan, Shivalila Chikdu S, Abraham Brian J, Latourelle Jeanne C, Barrasa M Inmaculada, Goldmann Johanna, Myers Richard H, Young Richard A, Jaenisch Rudolf

Replication fork progression during re-replication requires the DNA damage checkpoint and double-strand break repair

在重复复制过程中,复制叉的延伸需要DNA损伤检查点和双链断裂修复机制。

Alexander, Jessica L; Barrasa, M Inmaculada; Orr-Weaver, Terry L

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells

Tet酶的缺失会损害胚胎干细胞的正常分化。

Dawlaty, Meelad M; Breiling, Achim; Le, Thuc; Barrasa, M Inmaculada; Raddatz, Günter; Gao, Qing; Powell, Benjamin E; Cheng, Albert W; Faull, Kym F; Lyko, Frank; Jaenisch, Rudolf

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

Tet1和Tet2的联合缺乏会导致表观遗传异常,但不影响出生后的发育。

Dawlaty, Meelad M; Breiling, Achim; Le, Thuc; Raddatz, Günter; Barrasa, M Inmaculada; Cheng, Albert W; Gao, Qing; Powell, Benjamin E; Li, Zhe; Xu, Mingjiang; Faull, Kym F; Lyko, Frank; Jaenisch, Rudolf

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia

人类T细胞急性淋巴细胞白血病中由TAL1复合物控制的核心转录调控回路

Sanda, Takaomi; Lawton, Lee N; Barrasa, M Inmaculada; Fan, Zi Peng; Kohlhammer, Holger; Gutierrez, Alejandro; Ma, Wenxue; Tatarek, Jessica; Ahn, Yebin; Kelliher, Michelle A; Jamieson, Catriona H M; Staudt, Louis M; Young, Richard A; Look, A Thomas

A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors

多参数网络分析揭示了秀丽隐杆线虫bHLH转录因子之间广泛的差异

Grove, Christian A; De Masi, Federico; Barrasa, M Inmaculada; Newburger, Daniel E; Alkema, Mark J; Bulyk, Martha L; Walhout, Albertha J M

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.

秀丽隐杆线虫基因组规模的microRNA网络包含具有高通量能力的复合反馈基序

Martinez Natalia J, Ow Maria C, Barrasa M Inmaculada, Hammell Molly, Sequerra Reynaldo, Doucette-Stamm Lynn, Roth Frederick P, Ambros Victor R, Walhout Albertha J M

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans.

FLYWCH 转录因子 FLH-1、FLH-2 和 FLH-3 抑制秀丽隐杆线虫胚胎中 microRNA 基因的表达

Ow Maria C, Martinez Natalia J, Olsen Philip H, Silverman Howard S, Barrasa M Inmaculada, Conradt Barbara, Walhout Albertha J M, Ambros Victor