日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis

老年杏仁核对精制饮食的独特敏感性,与脂肪或糖含量无关:一项针对特定脑区和细胞类型的分析

Butler, Michael J; Blackwell, Jade A; Sanchez, Andrew A; Sanders, Hannah F; Kolonay, Dominic W; Jantsch, Jeferson; Muscat, Stephanie M; Caetano-Silva, Maria Elisa; Shrestha, Akriti; Yun Lim, Casey Kin; Mackey-Alfonso, Sabrina E; Alvarez, Bryan D; McCusker, Robert H; Allen, Jacob M; Baskin, Kedryn K; Barrientos, Ruth M

Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats

老年大鼠阿片类药物诱发的术后认知功能障碍的根本原因是海马线粒体功能紊乱。

Muscat, Stephanie M; Deems, Nicholas P; Alvarez, Bryan D; Butler, Michael J; Gonzalez Olmo, Brigitte M; Kolonay, Dominic W; Sanders, Hannah F; Scaria, Emmanuel A; Mackey-Alfonso, Sabrina E; Blackwell, Jade A; DeMarsh, James W; Bettes, Menaz N; Quach, Tam T; Cortese, Giuseppe P; Glasper, Erica R; Leuner, Benedetta; Baskin, Kedryn K; Barrientos, Ruth M

Neuroinflammatory mechanisms linking high-fat diets to Alzheimer's disease vulnerability: Beyond the amyloid hypothesis

高脂饮食与阿尔茨海默病易感性之间的神经炎症机制:超越淀粉样蛋白假说

Mackey-Alfonso, Sabrina E; Barrientos, Ruth M

Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats

肥胖相关的记忆障碍和神经炎症先于老年大鼠广泛的外周紊乱出现。

Butler, Michael J; Muscat, Stephanie M; Caetano-Silva, Maria Elisa; Shrestha, Akriti; Olmo, Brigitte M González; Mackey-Alfonso, Sabrina E; Massa, Nashali; Alvarez, Bryan D; Blackwell, Jade A; Bettes, Menaz N; DeMarsh, James W; McCusker, Robert H; Allen, Jacob M; Barrientos, Ruth M

Ligature-induced periodontitis in a transgenic mouse model of Alzheimer's disease dysregulates neuroinflammation, exacerbates cognitive impairment, and accelerates amyloid pathology.

在阿尔茨海默病转基因小鼠模型中,结扎诱导的牙周炎会扰乱神经炎症,加剧认知障碍,并加速淀粉样蛋白病理的发生

Jimenez-Harrison Daniela M, Butler Michael J, Ijaz Haanya, Alsabbagh Rami, Bettes Menaz N, DeMarsh James W, Mackey-Alfonso Sabrina E, Muscat Stephanie M, Alvarez Bryan D, Blackwell Jade A, Taylor Ashton, Jantsch Jeferson, Sanchez Andrew A, Peters Sarah B, Barrientos Ruth M

AI-based decoding of long covid cognitive impairments in mice using automated behavioral system and comparative transcriptomic analysis

利用自动化行为系统和比较转录组分析,基于人工智能解码小鼠新冠长期认知障碍

Amer, Heba M; Shamseldin, Mohamed M; Faber, Sarah; Eltobgy, Mostafa; Webb, Amy; El-Mergawy, Rabab; Chamblee, Michelle; Perez, Richard; Whitham, Owen; Badr, Asmaa; Gupta, Gauruv; Omran, Jihad; Bissel, Destiny; Yount, Jacob; Cormet-Boyaka, Estelle; Boyaka, Prosper N; Li, Jianrong; Zhang, Xiaoli; Peeples, Mark E; Mahesh, K C; Pietrzak, Maciej; Seveau, Stephanie; Kokiko-Cochran, Olga; Amer, Magdi; Barrientos, Ruth M; Schamess, Andrew; Oltz, Eugene; Amer, Amal O

Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementation

高脂饮食通过 TLR4 途径加剧术后认知功能障碍,而膳食补充 DHA 则可预防该障碍。

Muscat, Stephanie M; Butler, Michael J; Bettes, Menaz N; DeMarsh, James W; Scaria, Emmanuel A; Deems, Nicholas P; Barrientos, Ruth M

Short-term high fat diet impairs memory, exacerbates the neuroimmune response, and evokes synaptic degradation via a complement-dependent mechanism in a mouse model of Alzheimer's disease.

短期高脂肪饮食会损害记忆力,加剧神经免疫反应,并通过补体依赖机制在阿尔茨海默病小鼠模型中引发突触退化。

Mackey-Alfonso Sabrina E, Butler Michael J, Taylor Ashton M, Williams-Medina Alberto R, Muscat Stephanie M, Fu Hongjun, Barrientos Ruth M

Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling

短期高脂饮食会通过IL-1信号通路损害老年海马体的突触可塑性。

González Olmo, Brigitte M; Bettes, Menaz N; DeMarsh, James W; Zhao, Fangli; Askwith, Candice; Barrientos, Ruth M

Dietary DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined carbohydrates

膳食中的DHA可预防以精制碳水化合物为主食的老年雄性大鼠的认知障碍和炎症基因表达。

Butler, Michael J; Deems, Nicholas P; Muscat, Stephanie; Butt, Christopher M; Belury, Martha A; Barrientos, Ruth M