日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinatorial synthesis of a hyaluronan based polysaccharide library for enhanced CD44 binding

利用组合合成法构建基于透明质酸的多糖库以增强CD44结合能力

Kunli Liu ,William M McCue ,Chia-Wei Yang ,Barry C Finzel ,Xuefei Huang

Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314

基于肽 AcVDVAD-CHO 和 Caspase-2 介导的 Tau 裂解序列 YKPVD314 的新型 Caspase-2 抑制剂的结构设计和生物学评价

Merlin Bresinsky, Jessica M Strasser, Bernadette Vallaster, Peng Liu, William M McCue, Jessica Fuller, Alexander Hubmann, Gurpreet Singh, Kathryn M Nelson, Matthew E Cuellar, Carrie M Wilmot, Barry C Finzel, Karen H Ashe, Michael A Walters, Steffen Pockes

Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis

根据 caspase-2 介导的蛋白水解的特定位点表征 caspase-2 抑制剂

Merlin Bresinsky, Jessica M Strasser, Alexander Hubmann, Bernadette Vallaster, William M McCue, Jessica Fuller, Gurpreet Singh, Kathryn M Nelson, Matthew E Cuellar, Barry C Finzel, Karen H Ashe, Michael A Walters, Steffen Pockes

Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis

基于结构的优化,针对结核分枝杆菌中的生物素生物合成的吡哆醛 5'-磷酸依赖性转氨酶 (BioA) 抑制剂

Feng Liu, Surendra Dawadi, Kimberly M Maize, Ran Dai, Sae Woong Park, Dirk Schnappinger, Barry C Finzel, Courtney C Aldrich

Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors

利用核苷类双底物腺苷酸化抑制剂靶向结核分枝杆菌生物素蛋白连接酶 (MtBPL)

Matthew R Bockman #, Alvin S Kalinda #, Riccardo Petrelli, Teresa De la Mora-Rey, Divya Tiwari, Feng Liu, Surrendra Dawadi, Madhumitha Nandakumar, Kyu Y Rhee, Dirk Schnappinger, Barry C Finzel, Courtney C Aldrich

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis

基于靶标的结核分枝杆菌全细胞生物素生物合成活性抑制剂鉴定

Sae Woong Park, Dominick E Casalena, Daniel J Wilson, Ran Dai, Partha P Nag, Feng Liu, Jim P Boyce, Joshua A Bittker, Stuart L Schreiber, Barry C Finzel, Dirk Schnappinger, Courtney C Aldrich

Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily

人类组氨酸三联核苷酸结合蛋白 2(组氨酸三联超家族成员)的结构表征

Kimberly M Maize, Carston R Wagner, Barry C Finzel

Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis

参与结核分枝杆菌生物素生物合成的转氨酶 BioA 的基于机制的失活

Ce Shi, Todd W Geders, Sae Woong Park, Daniel J Wilson, Helena I Boshoff, Orishadipe Abayomi, Clifton E Barry 3rd, Dirk Schnappinger, Barry C Finzel, Courtney C Aldrich