LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model.
在基于 iPSC 的帕金森病模型中，LRRK2 突变的小胶质细胞和神经黑色素协同作用，驱动多巴胺能神经退行性变
期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08544-4
Blasco-Agell Lucas, Pons-Espinal Meritxell, Testa Veronica, Roch Gerard, Montero-Muñoz Jara, Fernandez-Carasa Irene, Baruffi Valentina, Gonzalez-Sepulveda Marta, Richaud-Patin Yvonne, Jimenez Senda, Cuadros Thais, Cladera-Sastre Joana M, Compte Joan, Manglano-Artuñedo Zoe, Ventura Salvador, Juan Manel, Tolosa Eduardo, Raya Angel, Vila Miquel, Consiglio Antonella
