日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CRISPR/Cas9 gene therapy increases the risk of tumorigenesis in the mouse model of hereditary tyrosinemia type I.

CRISPR/Cas9 基因疗法增加了 I 型遗传性酪氨酸血症小鼠模型发生肿瘤的风险

期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2025.101327
Chen Tong, Barzi Mercedes, Furey Nika, Kim Hyunjae R, Pankowicz Francis P, Legras Xavier, Elsea Sara H, Hurley Ayrea E, Yang Diane, Wheeler David A, Borowiak Malgorzata, Bissig-Choisat Beatrice, Sumazin Pavel, Bissig Karl-Dimiter
肿瘤
Mouse
肿瘤免疫
发表日期：2025
文献求助 收藏

Dissecting the effect of mitochondrial BCAT inhibition in methylmalonic acidemia.

剖析线粒体 BCAT 抑制对甲基丙二酸血症的影响。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.187758
Hemmingsen Madeline G, Zhang Guo-Fang, Ma Yunhan, Marchuk Hannah, Patel Kalyani R, Chen Tong, Li Xinning, Chapman Mark, Collias Sabrina, Lopez-Terrada Dolores H, Beasley James, Stiles Ashlee R, Chandler Randy J, Venditti Charles P, Young Sarah P, Barzi Mercedes, Bissig-Choisat Beatrice, Krafte Doug, Newgard Christopher B, Bissig Karl-Dimiter
线粒体
发表日期：2025
文献求助 收藏

High-potency MyoAAV capsids enhanced skeletal muscle correction in a mouse model of GSD IIIa

高活性MyoAAV衣壳增强了GSD IIIa小鼠模型的骨骼肌矫正效果

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2025.101567
Liao, Kuo-An; Han, Sang-Oh; Barzi, Mercedes; Yi, Haiqing; Eisner, William; Bissig-Choisat, Beatrice; Bissig, Karl-Dimiter; Sun, Baodong
发表日期：2025
文献求助 收藏

Ex vivo gene editing and cell therapy for hereditary tyrosinemia type 1

体外基因编辑和细胞疗法治疗1型遗传性酪氨酸血症

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000424
Ates, Ilayda; Stuart, Callie; Rathbone, Tanner; Barzi, Mercedes; He, Gordon; Major, Angela M; Shankar, Vijay; Lyman, Rachel A; Angner, Sidney S; Mackay, Trudy F C; Srinivasan, Shanthi; Farris, Alton Brad; Bissig, Karl-Dimiter; Cottle, Renee N
细胞生物学
发表日期：2024
文献求助 收藏

A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome

一种具有条件性重组游离基因组的乙型肝炎病毒转基因小鼠模型

期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2021.100252
Kruse, Robert L; Barzi, Mercedes; Legras, Xavier; Pankowicz, Francis P; Furey, Nika; Liao, Lan; Xu, Janming; Bissig-Choisat, Beatrice; Slagle, Betty L; Bissig, Karl-Dimiter
微生物学
肝炎
发表日期：2021
文献求助 收藏

A human liver chimeric mouse model for non-alcoholic fatty liver disease

用于研究非酒精性脂肪肝疾病的人类肝脏嵌合小鼠模型

期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2021.100281
Bissig-Choisat, Beatrice; Alves-Bezerra, Michele; Zorman, Barry; Ochsner, Scott A; Barzi, Mercedes; Legras, Xavier; Yang, Diane; Borowiak, Malgorzata; Dean, Adam M; York, Robert B; Galvan, N Thao N; Goss, John; Lagor, William R; Moore, David D; Cohen, David E; McKenna, Neil J; Sumazin, Pavel; Bissig, Karl-Dimiter
脂肪肝
代谢
发表日期：2021
文献求助 收藏

Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection

Cre/LoxP-HBV质粒在转染后产生重组共价闭合环状DNA基因组

期刊:Virus Research
影响因子:2.7
doi:10.1016/j.virusres.2020.198224
Kruse, Robert L; Legras, Xavier; Barzi, Mercedes
发表日期：2021
文献求助 收藏

Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

去甲肾上腺素再摄取抑制剂阿托莫西汀的代谢谱分析

期刊:European Journal of Pharmaceutical Sciences
影响因子:4.7
doi:10.1016/j.ejps.2020.105488
MacKenzie, Kevin R; Zhao, Mingkun; Barzi, Mercedes; Wang, Jin; Bissig, Karl-Dimiter; Maletic-Savatic, Mirjana; Jung, Sung Yun; Li, Feng
代谢
免疫/内分泌
发表日期：2020
文献求助 收藏

Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing

利用多重CRISPR/Cas9编辑技术快速特异性地破坏小鼠肝脏中的基因

期刊:Gastroenterology
影响因子:25.1
doi:10.1053/j.gastro.2018.08.037
Pankowicz, Francis P; Barzi, Mercedes; Kim, Kang Ho; Legras, Xavier; Martins, Celeste Santos; Wooton-Kee, Clavia Ruth; Lagor, William R; Marini, Juan C; Elsea, Sarah H; Bissig-Choisat, Beatrice; Moore, David D; Bissig, Karl-Dimiter
发表日期：2018
文献求助 收藏

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

HBsAg重定向的T细胞在HBV感染的人肝嵌合小鼠中表现出抗病毒活性。

期刊:Cytotherapy
影响因子:3.2
doi:10.1016/j.jcyt.2018.02.002
Kruse, Robert L; Shum, Thomas; Tashiro, Haruko; Barzi, Mercedes; Yi, Zhongzhen; Whitten-Bauer, Christina; Legras, Xavier; Bissig-Choisat, Beatrice; Garaigorta, Urtzi; Gottschalk, Stephen; Bissig, Karl-Dimiter
T细胞
炎症/感染
微生物学
T细胞
细胞生物学
免疫/内分泌
发表日期：2018
文献求助 收藏