日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of Toll-like Receptor 4 Using Small Molecule, TAK-242, Protects Islets from Innate Immune Responses

使用小分子 TAK-242 抑制 Toll 样受体 4,保护胰岛免受先天免疫反应的影响

Jordan Mattke, Carly M Darden, Srividya Vasu, Michael C Lawrence, Jeffrey Kirkland, Robert R Kane, Bashoo Naziruddin

Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress

钙调磷酸酶/NFATc2 和 PI3K/AKT 信号通路在代谢和炎症应激期间维持 β 细胞的特性和功能。

Carly M Darden ,Srividya Vasu ,Jordan Mattke ,Yang Liu ,Christopher J Rhodes ,Bashoo Naziruddin ,Michael C Lawrence

Withaferin A inhibits lymphocyte proliferation, dendritic cell maturation in vitro and prolongs islet allograft survival

醉茄素 A 可抑制淋巴细胞增殖、树突状细胞体外成熟并延长胰岛移植存活率

Kenjiro Kumano #, Mazhar A Kanak #, Prathab Balaji Saravanan, J P Blanck, Yang Liu, Srividya Vasu, Michael Lawrence, Bashoo Naziruddin

Pancreatic β-Cell-Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation

胰腺 β 细胞衍生的 IP-10/CXCL10 Isletokine 介导胰岛细胞移植中移植功能的早期丧失

Gumpei Yoshimatsu, Faisal Kunnathodi, Prathab Balaji Saravanan, Rauf Shahbazov, Charles Chang, Carly M Darden, Sandra Zurawski, Gulbahar Boyuk, Mazhar A Kanak, Marlon F Levy, Bashoo Naziruddin, Michael C Lawrence

Alleviation of instant blood-mediated inflammatory reaction in autologous conditions through treatment of human islets with NF-κB inhibitors

通过使用 NF-κB 抑制剂治疗人类胰岛来缓解自体条件下的即时血液介导炎症反应

Mazhar A Kanak, Morihito Takita, Takeshi Itoh, Jeffrey A SoRelle, Shyam Murali, Faisal Kunnathodi, Rauf Shahbazov, Michael C Lawrence, Marlon F Levy, Bashoo Naziruddin

A new method for generating insulin-secreting cells from human pancreatic epithelial cells after islet isolation transformed by NeuroD1

经 NeuroD1 转化的人胰岛分离后胰腺上皮细胞产生胰岛素分泌细胞的新方法

Masayuki Shimoda, Shuyuan Chen, Hirofumi Noguchi, Morihito Takita, Koji Sugimoto, Takeshi Itoh, Daisuke Chujo, Shuichi Iwahashi, Bashoo Naziruddin, Marlon F Levy, Shinichi Matsumoto, Paul A Grayburn