日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

帕立骨化醇和羟氯喹增强胰腺导管腺癌化疗疗效的机制

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2024.101881
Ganji Purnachandra Nagaraju ，Madhu Sudhana Saddala ，Jeremy B Foote ，Ateeq M Khaliq ，Ashiq Masood ，Yuvasri Golivi ，Dhana Sekhar Reddy Bandi ，Sujith Sarvesh ，Sudhir Putty Reddy ，Jeffrey Switchenko ，Julienne L Carstens ，Mehmet Akce ，Cameron Herting ，Olatunji B Alese ，Karina J Yoon ，Upender Manne ，Manoj K Bhasin ，Gregory B Lesinski ，Vikas P Sukhatme ，Bassel F El-Rayes
肿瘤
肿瘤免疫
发表日期：2025
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Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

PAK4 抑制剂 KPT9274 在 KRASG12C 突变型胰腺癌和肺癌临床前模型中增强了 KRASG12C 抑制剂的抗癌功效

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-23-0251
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Sahar F Bannoura, Yousef Mzannar, Ibrahim Azar, Eliza W Beal, Miguel E Tobon, Steve H Kim, Rafic Beydoun, Erkan Baloglu, William Senapedis, Bassel F El-Rayes, Philip A Philip, Ramzi M Mohammad, Anthony F Shields, Moh
代谢
肿瘤
肺癌
胰腺癌
FCM
IF
IHC-P
WB
Human
G3P
发表日期：2023
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A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186

帕博利珠单抗 (MK-3475) 联合化疗治疗晚期结直肠癌患者的多中心、单组 Ib 期临床研究：HCRN GI14-186

期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-021-02986-5
Cameron J Herting #, Matthew R Farren #, Yan Tong, Ziyue Liu, Bert O'Neil, Tanios Bekaii-Saab, Anne Noonan, Christopher McQuinn, Thomas A Mace, Walid Shaib, Christina Wu, Bassel F El-Rayes, Safi Shahda, Gregory B Lesinski
肿瘤
肠癌
发表日期：2021
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PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

PAK4-NAMPT 双重抑制增强胰腺神经内分泌肿瘤对依维莫司的敏感性

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-20-1105
Gabriel B Mpilla, Md Hafiz Uddin, Mohammed N Al-Hallak, Amro Aboukameel, Yiwei Li, Steve H Kim, Rafic Beydoun, Gregory Dyson, Erkan Baloglu, William T Senapedis, Yosef Landesman, Kay-Uwe Wagner, Nerissa T Viola, Bassel F El-Rayes, Philip A Philip, Ramzi M Mohammad, Asfar S Azmi
神经
肿瘤
胰腺癌
WB
ACTC
发表日期：2021
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Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer

热休克蛋白 90 抑制可改变胰腺星状细胞的活化并增强 PD-1 阻断对胰腺癌的疗效

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-19-0911
Yuchen Zhang, Michael B Ware, Mohammad Y Zaidi, Amanda N Ruggieri, Brian M Olson, Hannah Komar, Matthew R Farren, Ganji Purnachandra Nagaraju, Chao Zhang, Zhengjia Chen, Juan M Sarmiento, Rafi Ahmed, Shishir K Maithel, Bassel F El-Rayes, Gregory B Lesinski
代谢
肿瘤
胰腺癌
其它细胞
发表日期：2021
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Napabucasin (BBI 608), a potent chemoradiosensitizer in rectal cancer

Napabucasin (BBI 608)，一种治疗直肠癌的强效放化疗增敏剂

期刊:Cancer
影响因子:6.1
doi:10.1002/cncr.32954
Ganji Purnachandra Nagaraju, Batoul Farran, Matthew Farren, Gayathri Chalikonda, Christina Wu, Gregory B Lesinski, Bassel F El-Rayes
肿瘤
肠癌
FCM
IF
IHC-P
WB
MDM2
发表日期：2020
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Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer

抑制 HSP90 可克服胰腺癌对化疗和放疗的耐药性

期刊:International Journal of Cancer
影响因子:5.7
doi:10.1002/ijc.32227
Ganji Purnachandra Nagaraju, Katerina M Zakka, Jerome C Landry, Walid L Shaib, Gregory B Lesinski, Bassel F El-Rayes
代谢
肿瘤
胰腺癌
发表日期：2019
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Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells

抑制热休克蛋白 90 和泛素-蛋白酶体通路会破坏代谢稳态并导致人类胰腺癌细胞死亡

期刊:Cancer
影响因子:6.1
doi:10.1002/cncr.30944
Astrid Belalcazar, Walid L Shaib, Matthew R Farren, Chao Zhang, Zhengjia Chen, Lily Yang, Gregory B Lesinski, Bassel F El-Rayes, Ganji Purnachandra Nagaraju
代谢
信号转导
细胞生物学
肿瘤
胰腺癌
肿瘤细胞
Human
发表日期：2017
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High nuclear hypoxia-inducible factor 1 alpha expression is a predictor of distant recurrence in patients with resected pancreatic adenocarcinoma

核缺氧诱导因子 1α 高表达是切除胰腺腺癌患者远处复发的预测因素

期刊:International Journal of Radiation Oncology Biology Physics
影响因子:6.4
doi:10.1016/j.ijrobp.2014.11.004
Lauren E Colbert, Sarah B Fisher, Serdar Balci, Burcu Saka, Zhengjia Chen, Sungjin Kim, Bassel F El-Rayes, N Volkan Adsay, Shishir K Maithel, Jerome C Landry, Walter J Curran Jr
肿瘤
胰腺癌
HIF1A
发表日期：2015
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CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer

CHD7 表达可预测胰腺癌切除术后患者的生存结果

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-13-1996
Lauren E Colbert, Aleksandra V Petrova, Sarah B Fisher, Brooke G Pantazides, Matthew Z Madden, Claire W Hardy, Matthew D Warren, Yunfeng Pan, Ganji P Nagaraju, Elaine A Liu, Burcu Saka, William A Hall, Joseph W Shelton, Khanjan Gandhi, Rini Pauly, Jeanne Kowalski, David A Kooby, Bassel F El-Rayes, C
代谢
肿瘤
胰腺癌
FCM
IF
IHC-P
WB
CHK1
发表日期：2014
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