Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope
通过靶向近膜表位可以克服因脱落的间皮素结合而引起的肿瘤对抗间皮素 CAR-T 细胞的耐药性
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.2317283121
X F Liu, M Onda, J Schlomer, L Bassel, S Kozlov, C-H Tai, Q Zhou, W Liu, H-E Tsao, R Hassan, M Ho, I Pastan
