日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination.

启动子和增强子依赖的黏连蛋白加载启动染色体环化,使 Tcrb 基因座折叠起来进行长程重组。

Allyn Brittney M, Hayer Katharina E, Oyeniran Clement, Nganga Vincent, Lee Kyutae, Sacan Ahmet, Oltz Eugene M, Bassing Craig H

Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development

内含子调控元件对连接酶IV的转录调控指导胸腺细胞发育

Matthew D Estrada # ,Christopher J Gebhardt # ,Mariam A Salem ,Christina N Rau ,Kruthika Sharma ,Rebecca A Glynn ,Craig H Bassing ,Eugene M Oltz ,Patrick L Collins

Transcriptional regulation of the non-homologous end joining gene Ligase IV by an intronic regulatory element directs thymocyte development

非同源末端连接基因连接酶IV的转录调控受内含子调控元件的调控,从而指导胸腺细胞发育。

Estrada, Matthew D; Gebhardt, Christopher J; Salem, Mariam; Sharma, Kruthika; Bassing, Craig H; Oltz, Eugene M; Collins, Patrick L

Locus folding mechanisms determine modes of antigen receptor gene assembly

基因座折叠机制决定抗原受体基因组装模式

Brittney M Allyn, Katharina E Hayer, Clement Oyeniran, Vincent Nganga, Kyutae Lee, Bikash Mishra, Ahmet Sacan, Eugene M Oltz, Craig H Bassing

The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein-Signaled Feedback Inhibition of Vβ Recombination

细胞周期蛋白 D3 蛋白通过介导 TCRβ 蛋白信号反馈抑制 Vβ 重组来促进单基因 TCRβ 表达

Erica J Culberson, Kymberle C Shields, Rebecca A Glynn, Brittney M Allyn, Katharina E Hayer, Craig H Bassing

ATM-dependent Phosphorylation of Nemo SQ Motifs Is Dispensable for Nemo-mediated Gene Expression Changes in Response to DNA Double-Strand Breaks.

ATM 依赖的 Nemo SQ 基序磷酸化对于 Nemo 介导的基因表达变化响应 DNA 双链断裂而言并非必需

Glynn Rebecca A, Hayer Katharina E, Bassing Craig H

Monogenic TCRβ Assembly and Expression Are Paramount for Uniform Antigen Receptor Specificity of Individual αβ T Lymphocytes

单基因 TCRβ 组装和表达对于单个 αβ T 淋巴细胞的统一抗原受体特异性至关重要

Erica J Culberson, Craig H Bassing

Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks at Igk Feedback Inhibit V κ Recombination to Enforce Igκ Allelic Exclusion

Nemo依赖的、ATM介导的RAG DNA断裂信号通过Igk反馈抑制Vκ重组,从而强制Igκ等位基因排斥

Rebecca A Glynn ,Craig H Bassing

Poor-Quality Vβ Recombination Signal Sequences and the DNA Damage Response ATM Kinase Collaborate to Establish TCRβ Gene Repertoire and Allelic Exclusion

低质量的Vβ重组信号序列和DNA损伤反应ATM激酶协同作用,建立TCRβ基因库和等位基因排斥。

Wu, Glendon S; Culberson, Erica J; Allyn, Brittney M; Bassing, Craig H

The RAG1 Ubiquitin Ligase Domain Stimulates Recombination of TCRβ and TCRα Genes and Influences Development of αβ T Cell Lineages

RAG1泛素连接酶结构域刺激TCRβ和TCRα基因的重组并影响αβ T细胞谱系的发育

Burn, Thomas N; Miot, Charline; Gordon, Scott M; Culberson, Erica J; Diamond, Tamir; Kreiger, Portia A; Hayer, Katharina E; Bhattacharyya, Anamika; Jones, Jessica M; Bassing, Craig H; Behrens, Edward M