日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy

利用炎症性单核细胞克服抗PD-1免疫疗法的耐药性

Zimmerman, Matthew P; Huang, Amy Y; Cox, Emily K; Al Abosy, Rose; Chong, Wan Lin; Bastian, Alexander G; Vietor, Katherine; Choutri, Yacine; Collier, Jenna; Zhabotynsky, Vasyl; Wang, Haiyang; Fung, Megan; Weiss, Sarah A; Robitschek, Emily J; Lin, Jia-Ren; Vallius, Tuulia; Pant, Shishir M; Sorger, Peter K; Hugo, Willy; Sen, Debattama R; Haining, W Nicholas; Sharpe, Arlene H; Miller, Brian C

Structure-guided design and engineering of a biparatopic antibody targeting CCR2 in triple negative breast cancer.

针对三阴性乳腺癌中 CCR2 的结构导向设计和工程化双位点抗体。

Little Timothy S, Wang Yuyan, Chaudhari Ameya P, Budayr Omar M, Tetterton-Kellner Jessica G, Bastian Alexander G, Brown Adam D, Jasiewicz Natalie E, McCue Amelia C, Earp H Shelton, Miller Brian C, Nguyen Juliane

A Novel Antiviral Therapeutic Platform: Anchoring IFN-β to the Surface of Infectious Virions Equips Interferon-Evasive Virions with Potent Antiviral Activity.

一种新型抗病毒治疗平台:将 IFN-β 锚定到感染性病毒颗粒表面,使逃避干扰素的病毒颗粒具有强大的抗病毒活性

Jabbour Hoda H, Bastian Alexander G, DeOca Kayla B, Mannie Mark D

A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4(+) CD25(+) FOXP3(+) Tregs that inhibit experimental autoimmune encephalomyelitis (EAE)

GM-CSF-神经抗原耐受性疫苗可引发低于CD40L触发阈值的低效抗原识别事件,从而扩增CD4(+)CD25(+)FOXP3(+)调节性T细胞,抑制实验性自身免疫性脑脊髓炎(EAE)。

Moorman, Cody D; Bastian, Alexander G; DeOca, Kayla B; Mannie, Mark D

Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3(+) regulatory T cells

耐受性疫苗:靶向FOXP3(+)调节性T细胞的抗原和细胞因子微环境

Mannie, Mark D; DeOca, Kayla B; Bastian, Alexander G; Moorman, Cody D