日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pulsed stimuli enable p53 phase resetting to synchronize single cells and modulate cell fate

脉冲刺激可使p53相位重置,从而同步单个细胞并调节细胞命运。

Venkatachalapathy, Harish; Dallon, Samuel; Yang, Zhilin; Azarin, Samira M; Sarkar, Casim A; Batchelor, Eric

Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome.

MYC拓扑体活性过高会引发急性DNA损伤、MYC降解,并被p53拓扑体取代

Das Subhendu K, Karmakar Sharmistha, Venkatachalapathy Harish, Jha Rajiv Kumar, Batchelor Eric, Levens David

Inertial effect of cell state velocity on the quiescence-proliferation fate decision

细胞状态速度的惯性效应对静止-增殖命运决定的影响

Venkatachalapathy, Harish; Brzakala, Cole; Batchelor, Eric; Azarin, Samira M; Sarkar, Casim A

Inertial effect of cell state velocity on the quiescence-proliferation fate decision in breast cancer

细胞状态速度的惯性效应对乳腺癌细胞静止-增殖命运决定的影响

Venkatachalapathy, Harish; Brzakala, Cole; Batchelor, Eric; Azarin, Samira M; Sarkar, Casim A

Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency

乙酰胆碱在基底外侧杏仁核中释放,以响应奖励预测信号,并增强对线索-奖励关联性的学习。

Richard B Crouse,Kristen Kim,Hannah M Batchelor,Eric M Girardi,Rufina Kamaletdinova,Justin Chan,Prithviraj Rajebhosale,Steven T Pittenger,Lorna W Role,David A Talmage,Miao Jing,Yulong Li,Xiao-Bing Gao,Yann S Mineur,Marina R Picciotto

Determining the Limitations and Benefits of Noise in Gene Regulation and Signal Transduction through Single Cell, Microscopy-Based Analysis

通过单细胞显微镜分析确定噪声在基因调控和信号转导中的局限性和益处

Harton, Marie D; Batchelor, Eric

p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks.

p53脉冲以mRNA半衰期依赖的方式使靶基因表达动态多样化,并勾勒出共调控的靶基因子网络

Porter Joshua R, Fisher Brian E, Batchelor Eric

Using computational modeling and experimental synthetic perturbations to probe biological circuits

利用计算建模和实验合成扰动来探测生物回路

Porter, Joshua R; Batchelor, Eric

Stimulus-dependent dynamics of p53 in single cells

单细胞中p53的刺激依赖性动态变化

Batchelor, Eric; Loewer, Alexander; Mock, Caroline; Lahav, Galit

A synthetic-natural hybrid oscillator in human cells

人类细胞中的合成-天然混合振荡器

Toettcher, Jared E; Mock, Caroline; Batchelor, Eric; Loewer, Alexander; Lahav, Galit