日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

田鼠朊病毒蛋白拓展了RT-QuIC检测方法在多种遗传性朊病毒疾病中检测朊病毒的应用范围。

Mok, Tze How; Nihat, Akin; Luk, Connie; Sequeira, Danielle; Batchelor, Mark; Mead, Simon; Collinge, John; Jackson, Graham S

Structural effects of the highly protective V127 polymorphism on human prion protein.

高度保护性的 V127 多态性对人类朊病毒蛋白的结构影响

Hosszu Laszlo L P, Conners Rebecca, Sangar Daljit, Batchelor Mark, Sawyer Elizabeth B, Fisher Stuart, Cliff Matthew J, Hounslow Andrea M, McAuley Katherine, Leo Brady R, Jackson Graham S, Bieschke Jan, Waltho Jonathan P, Collinge John

Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers

结蛋白会形成有毒的、具有播散能力的淀粉样蛋白聚集体,这些聚集体持续存在于肌肉纤维中。

Kedia, Niraja; Arhzaouy, Khalid; Pittman, Sara K; Sun, Yuanzi; Batchelor, Mark; Weihl, Conrad C; Bieschke, Jan

A systematic investigation of production of synthetic prions from recombinant prion protein

对利用重组朊病毒蛋白生产合成朊病毒的系统研究

Schmidt, Christian; Fizet, Jeremie; Properzi, Francesca; Batchelor, Mark; Sandberg, Malin K; Edgeworth, Julie A; Afran, Louise; Ho, Sammy; Badhan, Anjna; Klier, Steffi; Linehan, Jacqueline M; Brandner, Sebastian; Hosszu, Laszlo L P; Tattum, M Howard; Jat, Parmjit; Clarke, Anthony R; Klöhn, Peter C; Wadsworth, Jonathan D F; Jackson, Graham S; Collinge, John

N-terminal domain of prion protein directs its oligomeric association

朊病毒蛋白的N端结构域指导其寡聚化。

Trevitt, Clare R; Hosszu, Laszlo L P; Batchelor, Mark; Panico, Silvia; Terry, Cassandra; Nicoll, Andrew J; Risse, Emmanuel; Taylor, William A; Sandberg, Malin K; Al-Doujaily, Huda; Linehan, Jacqueline M; Saibil, Helen R; Scott, David J; Collinge, John; Waltho, Jonathan P; Clarke, Anthony R

Conformational properties of beta-PrP

β-PrP的构象特性

Hosszu, Laszlo L P; Trevitt, Clare R; Jones, Samantha; Batchelor, Mark; Scott, David J; Jackson, Graham S; Collinge, John; Waltho, Jonathan P; Clarke, Anthony R

Recombinant prion protein does not possess SOD-1 activity

重组朊病毒蛋白不具有SOD-1活性。

Jones, Samantha; Batchelor, Mark; Bhelt, Daljit; Clarke, Anthony R; Collinge, John; Jackson, Graham S