日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineered Receptor Capture Combined with Mass Spectrometry Enables High-Throughput Detection and Quantitation of SARS-CoV-2 Spike Protein

工程化受体捕获结合质谱技术可实现SARS-CoV-2刺突蛋白的高通量检测和定量。

Bate, Neil; Lane, Dan; Evans, Sian E; Salim, Farah; Allcock, Natalie S; Haigh, Richard; Sale, Julian E; Jones, Donald J L; Brindle, Nicholas P J

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding

体外进化预测了对ACE2具有高亲和力且能跨物种结合的SARS-CoV-2新出现的突变体。

Bate, Neil; Savva, Christos G; Moody, Peter C E; Brown, Edward A; Evans, Sian E; Ball, Jonathan K; Schwabe, John W R; Sale, Julian E; Brindle, Nicholas P J

Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain

Sin3A 通过高度保守的 Sin3 相互作用域将 Tet1 募集到 PAH1 结构域。

Chandru, Aditya; Bate, Neil; Vuister, Geerten W; Cowley, Shaun M

Subcellular localization of talin is regulated by inter-domain interactions

talin的亚细胞定位受结构域间相互作用调控。

Banno, Asoka; Goult, Benjamin T; Lee, HoSup; Bate, Neil; Critchley, David R; Ginsberg, Mark H

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.

Talin 含有一个 C 端钙蛋白酶 2 切割位点,该位点在粘着斑动力学中起重要作用

Bate Neil, Gingras Alexandre R, Bachir Alexia, Horwitz Rick, Ye Feng, Patel Bipin, Goult Benjamin T, Critchley David R

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

体内机械转导依赖于黏着斑蛋白,其通过重复的爪蛋白拉伸-松弛事件发挥作用。

Margadant, Felix; Chew, Li Li; Hu, Xian; Yu, Hanry; Bate, Neil; Zhang, Xian; Sheetz, Michael

The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site

talin的结构域:残基1815-1973形成一个五螺旋束,其中包含一个隐蔽的vinculin结合位点。

Goult, Benjamin T; Gingras, Alexandre R; Bate, Neil; Barsukov, Igor L; Critchley, David R; Roberts, Gordon C K

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

整合素/爪蛋白复合物的结构揭示了由内而外信号转导的基础

Anthis, Nicholas J; Wegener, Kate L; Ye, Feng; Kim, Chungho; Goult, Benjamin T; Lowe, Edward D; Vakonakis, Ioannis; Bate, Neil; Critchley, David R; Ginsberg, Mark H; Campbell, Iain D

The structure of the C-terminal actin-binding domain of talin

肌动蛋白结合域的结构

Gingras, Alexandre R; Bate, Neil; Goult, Benjamin T; Hazelwood, Larnele; Canestrelli, Ilona; Grossmann, J Günter; Liu, HongJun; Putz, Nicholas S M; Roberts, Gordon C K; Volkmann, Niels; Hanein, Dorit; Barsukov, Igor L; Critchley, David R