日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni

对甲氟喹-金属配合物中配体的研究揭示了其抗恶性疟原虫和曼氏血吸虫活性的结构决定因素

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c03739
Villarreal, Wilmer; Quadros, Helenita Costa; Colina-Vegas, Legna; Aboagye, Sammy Y; Dziwornu, Godwin Akpeko; Ribeiro, Gabriel H; Barros, Ariane Isis; Kucharski, Dawid Jakub; Rahbari, Mahsa; Brandstädter, Christina; D'Alessandro, Sarah; Basilico, Nicoletta; Masike, Keabetswe; Mehlala, Nandi; Nobrega, Joaquim Araújo; Deflon, Victor M; Navarro, Maribel; Boratyński, Przemysław J; Chibale, Kelly; Williams, David L; Batista, Alzir A; Moreira, Diogo R M
发表日期：2026
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Para-substituted benzoic acid ruthenium(ii) complexes: structural features modulating cytotoxicity

对位取代苯甲酸钌(II)配合物：调节细胞毒性的结构特征

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra07271a
Dutra, Jocely L; Marcon, Pedro H S; Moselli, Gustavo; Niquini, Fabiano M; da Costa, João Victor F; Moraes, Carlos André F; Braga, Ataualpa A C; Ellena, Javier; Batista, Alzir A; de Araujo-Neto, João Honorato
毒理研究
细胞生物学
发表日期：2026
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Synthesis and Structure Elucidation of New NSAID Diphosphine Ruthenium(II) Complexes as Potential Anticancer Agents: DNA/BSA Binding and Cytotoxicity Assays

新型非甾体抗炎药二膦钌(II)配合物的合成与结构解析及其作为潜在抗癌药物的应用：DNA/BSA结合和细胞毒性试验

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c12981
Carvalho, Diogo E L; Teixeira, Tamara; de Araujo-Neto, João Honorato; Batista, Alzir A; Fragoso, Keven S; Oliveira, Katia M; Corrêa, Rodrigo S
细胞生物学
肿瘤
肿瘤免疫
毒理研究
发表日期：2026
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Copper(II)-5-chloro-2-hydroxybenzophenone Complexes with N-N Donors: Structural Insights and Antitumor Activity against A2780 Human Ovarian Cancer Cells of a Bathophen Derivative

铜(II)-5-氯-2-羟基二苯甲酮与NN供体配合物：结构解析及对A2780人卵巢癌细胞的抗肿瘤活性研究（一种巴托芬衍生物）

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c11889
B de Carvalho, Alexandre; Palmeira-Mello, Marcos V; de Souza, Paulo N; Mendes Abe, Saulo H; Balena G Filho, José; Andrade, Marcelo B; Corrêa, Rodrigo S; Batista, Alzir A; Ellena, Javier
肿瘤
肿瘤免疫
卵巢癌
Human
细胞生物学
发表日期：2026
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Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Pd(II)-硫代氨基脲配合物增强的抗癌潜力：选择性、机制和三维模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17070829
Lima, Mauro A; Teixeira, Tamara; Fortaleza, Dario B; Pereira, George B S; Akinyemi, Amos O; Moraes, Carlos André Ferreira; Forim, Moacir R; Batista, Alzir A; Dutra, Jocely L; Araujo-Neto, João H; Ellena, Javier A; Rocha, Fillipe V
肿瘤
肿瘤免疫
发表日期：2025
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Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models.

Ru(II)-芬那酸基配合物作为有前景的人类卵巢抗肿瘤药物：DNA相互作用、细胞摄取和三维球体模型

期刊:Inorganic Chemistry
影响因子:4.7
doi:10.1021/acs.inorgchem.4c04344
Teixeira Tamara, Palmeira-Mello Marcos V, Machado Pedro Henrique, Moraes Carlos A F, Pinto Camila, Costa Rayane C, Badaró Wladimir, Gomes Neto José A, Ellena Javier, Vieira Rocha Fillipe, Batista Alzir A, Correa Rodrigo S
细胞生物学
肿瘤
Human
肿瘤免疫
发表日期：2025
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Structural and Anticancer Studies of Methoxyflavone Derivative from Strychnos pseudoquina A.St.-Hil. (Loganiaceae) from Brazilian Cerrado

巴西塞拉多草原植物假马钱子（Strychnos pseudoquina A.St.-Hil.，马钱科）甲氧基黄酮衍生物的结构和抗癌研究

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.3c05841
Silva, Marianna C; Cunha, Gracielle; Firmino, Pollyana; Sallum, Loide O; Menezes, Antônio; Dutra, Jocely; de Araujo-Neto, João; Batista, Alzir A; Ellena, Javier; Napolitano, Hamilton B
肿瘤
肿瘤免疫
发表日期：2023
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Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model.

钌配合物与哌啶通过 p53 依赖性通路激活 MAPK 信号，诱导人结肠癌细胞凋亡，并在异种移植模型中抑制肿瘤发展

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2019.00582
Baliza Ingrid R S, Silva Suellen L R, Santos Luciano de S, Neto João H Araujo, Dias Rosane B, Sales Caroline B S, Rocha Clarissa A Gurgel, Soares Milena B P, Batista Alzir A, Bezerra Daniel P
信号转导
细胞生物学
肿瘤
肠癌
Apoptosis
Human
P53
凋亡
发表日期：2019
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Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

新型含哌啶钌配合物：合成、细胞生长抑制、细胞凋亡诱导及对HCT116细胞活性氧（ROS）产生的影响

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.22248
D'Sousa Costa, Cinara O; Araujo Neto, João H; Baliza, Ingrid R S; Dias, Rosane B; Valverde, Ludmila de F; Vidal, Manuela T A; Sales, Caroline B S; Rocha, Clarissa A G; Moreira, Diogo R M; Soares, Milena B P; Batista, Alzir A; Bezerra, Daniel P
细胞生物学
凋亡
表观遗传
发表日期：2017
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Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death

硝基/亚硝酰基钌配合物是强效且选择性的抗克氏锥虫药物，可诱导自噬和寄生虫坏死死亡。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02765-14
Bastos, Tanira M; Barbosa, Marília I F; da Silva, Monize M; da C Júnior, José W; Meira, Cássio S; Guimaraes, Elisalva T; Ellena, Javier; Moreira, Diogo R M; Batista, Alzir A; Soares, Milena B P
微生物学
自噬
发表日期：2014
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