日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure, Function, and Inhibition of Adenylosuccinate Lyase (ADSL) from Mycobacterium tuberculosis

结核分枝杆菌腺苷酸琥珀酸裂解酶 (ADSL) 的结构、功能和抑制

Singh, Vigyasa; Jaganathan, Devi; Corro, Jamie; Chen, Ke; Kumar Samrat, Subodh; Zhang, Ran; Ma, Mengjiao; Battaile, Kevin P; Li, Zhong; Zhang, Qing-Yu; Xiong, Rui; Ojha, Anil K; Li, Hongmin

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor

发现并阐明了一种高选择性抗真菌乙酰辅酶A合成酶抑制剂的作用机制

Jezewski, Andrew J; Alden, Katy M; Propp, Jonah; Daraji, Drashti G; Lail, Charles L 3rd; Heene, Michael E; Fuller, Andrew J; Ferreira, Jeffery C; Liu, Lijun; Battaile, Kevin P; Williams, Noelle S; Staker, Bart L; Lovell, Scott; Hagen, Timothy J; Krysan, Damian J

Mechanistic studies of small molecule ligands selective to RNA single G bulges

对RNA单G凸起选择性小分子配体的机制研究

Hegde, Shalakha; Akhter, Sana; Tang, Zhichao; Qi, Chang; Yu, Chenguang; Lewicka, Anna; Liu, Yu; Koirala, Kushal; Reibarkh, Mikhail; Battaile, Kevin P; Cooper, Anne; Lovell, Scott; Holmstrom, Erik D; Wang, Xiao; Piccirilli, Joseph A; Gao, Qi; Miao, Yinglong; Wang, Jingxin

Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases

铜绿假单胞菌谷氨酰-tRNA合成酶的结构定义了二聚体Ib类氨酰-tRNA合成酶的一个亚家族。

Fenwick, Michael K; Mayclin, Stephen J; Seibold, Steve; DeRocher, Amy E; Subramanian, Sandhya; Phan, Isabelle Q; Dranow, David M; Lorimer, Donald D; Abramov, Ariel B; Choi, Ryan; Hewitt, Stephen Nakazawa; Edwards, Thomas E; Bullard, James M; Battaile, Kevin P; Wower, Iwona K; Soe, Aimee C; Tsutakawa, Susan E; Lovell, Scott; Myler, Peter J; Wower, Jacek; Staker, Bart L

Inhibitors of the Bacterioferritin Ferredoxin Complex Dysregulate Iron Homeostasis and Kill Acinetobacter baumannii and Biofilm-Embedded Pseudomonas aeruginosa Cells

细菌铁蛋白铁氧还蛋白复合物抑制剂会扰乱铁稳态并杀死鲍曼不动杆菌和生物膜包裹的铜绿假单胞菌细胞

Behm, Alexanndra M; Yao, Huili; Eze, Emmanuel C; Alli, Suliat A; Baugh, Simon D P; Ametsetor, Ebenezer; Powell, Kendall M; Battaile, Kevin P; Seibold, Steve; Lovell, Scott; Bunce, Richard A; Reitz, Allen B; Rivera, Mario

Charity coverage and decreased COVID-19 mortality among uninsured patients in Texas: A retrospective cohort study

慈善医疗覆盖与德克萨斯州无保险患者新冠肺炎死亡率降低:一项回顾性队列研究

Ganguly, Anisha P; Battaile, John T; Harms, Michael; Murray, Shannon; Gurley, Tami; Haley, Robert W; Jain, Mamta K; Bhavan, Kavita P

Crystal structures of Mycobacterium tuberculosis and Mycobacterium thermoresistibile glycyl-tRNA synthetases in various liganded states

结核分枝杆菌和耐热分枝杆菌甘氨酰-tRNA合成酶在不同配体结合状态下的晶体结构

Fenwick, Michael K; DeRocher, Amy E; Craig, Justin K; Harmon, Elizabeth K; Seibold, Steve; Liu, Lijun; Battaile, Kevin P; Barrett, Lynn K; Van Voorhis, Wesley C; Phan, Isabelle Q; Staker, Bart L; Subramanian, Sandhya; Lovell, Scott; Myler, Peter J

New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease

新型环孢菌素D抑制剂可挽救阿尔茨海默病患者的线粒体和认知功能

Sourav Samanta ,Firoz Akhter ,Anuradha Roy ,Doris Chen ,Benjamin Turner ,Yongfu Wang ,Nicolina Clemente ,Chunyu Wang ,Russell Howard Swerdlow ,Kevin P Battaile ,Scott Lovell ,Shi Fang Yan ,Shirley ShiDu Yan

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens.

合理探索 2,4-二氨基嘧啶作为 DHFR 抑制剂对脓肿分枝杆菌和鸟分枝杆菌(两种新兴人类病原体)的活性

Andrade Meirelles Matheus, Almeida Vitor M, Sullivan Jaryd R, de Toledo Ian, Dos Reis Caio Vinicius, Cunha Micael Rodrigues, Zigweid Rachel, Shim Abraham, Sankaran Banumathi, Woodward Elijah L, Seibold Steve, Liu Lijun, Mian Mohammad Rasel, Battaile Kevin P, Riley Jennifer, Duncan Christina, Simeons Frederick R C, Ferguson Liam, Joji Halimatu, Read Kevin D, Lovell Scott, Staker Bart L, Behr Marcel A, Pilli Ronaldo A, Couñago Rafael M

Mechanism-Based Macrocyclic Inhibitors of Serine Proteases.

基于机制的丝氨酸蛋白酶大环抑制剂

Damalanka Vishnu C, Banas Victoria, De Bona Paolo, Kashipathy Maithri M, Battaile Kevin, Lovell Scott, Janetka James W