日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A µ-opioid receptor superagonist analgesic with minimal adverse effects

一种μ-阿片受体超激动剂镇痛药,不良反应极小

Gomez, Juan L; Ventriglia, Emilya N; Frangos, Zachary J; Sulima, Agnieszka; Robertson, Michael J; Sacco, Michael D; Budinich, Reece C; Giosan, Ilinca M; Xie, Tongzhen; Solis, Oscar; Tischer, Anna E; Bossert, Jennifer M; Caldwell, Kiera E; Bonbrest, Hannah; Essmann, Amelie; Garçon-Poca, Zelai M; Choi, Shinbe; Noya, Michael R; Limiac, Feonil; Arce, Ali; Glatfelter, Grant C; Robinson, Margaret; Chen, Li; Mullarkey, Angelina A; Brademan, Dain R; Enten, Garrett; Dunne, William; Quiroz, César; Schoenborn, Ingrid; Lee, Chae Bin; Rais, Rana; Holt, Daniel P; Dannals, Robert F; Shi, Lei; Hüttenhain, Ruth; Ferré, Sergi; Kiyatkin, Eugene; Bonaventura, Jordi; Shaham, Yavin; Zachariou, Venetia; Baumann, Michael H; Skiniotis, Georgios; Rice, Kenner C; Michaelides, Michael

The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects

2,5-二甲氧基苯丙胺的4-烷基链长度对其体外血清素受体活性和体内迷幻样效应的影响不同。

Luethi, Dino; Glatfelter, Grant C; Pottie, Eline; Sellitti, Francesca; Maitland, Alexander D; Gonzalez, Nicholas R; Kryszak, Lindsay A; Jackson, Shelley N; Hoener, Marius C; Stove, Christophe P; Liechti, Matthias E; Smieško, Martin; Baumann, Michael H; Simmler, Linda D; Rudin, Deborah

Pharmacodynamic effects and plasma pharmacokinetics of N, N-dimethyltryptamine after intranasal versus subcutaneous administration in male rats

雄性大鼠鼻内给药与皮下给药后N,N-二甲基色胺的药效学效应和血浆药代动力学

Baumann, Michael H; Glatfelter, Grant C; Walton, Sara E; Krotulski, Alex J; Witowski, Christopher G; von Salm, Jacqueline L

Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences

脯氨酰胺类似物作为杂合单胺转运体配体:结构决定因素和物种差异

Kastner, Nina; Islam, Mohammad N; Dybek, Michael; Roth, Evelyn; Heisinger, Simon; Holy, Marion; Jäntsch, Kathrin; Walther, Donna; Stockner, Thomas; Baumann, Michael H; Brandt, Simon D; Wallach, Jason; Sitte, Harald H; Kudlacek, Oliver

Psychedelic-like effects induced by 2,5-dimethoxy-4-iodoamphetamine, lysergic acid diethylamide, and psilocybin in male and female C57BL/6J mice

2,5-二甲氧基-4-碘苯丙胺、麦角酸二乙酰胺和裸盖菇素在雄性和雌性C57BL/6J小鼠中诱导的迷幻样效应

McGriff, Shelby A; Hecker, Jacquelin C; Maitland, Alexander D; Partilla, John S; Baumann, Michael H; Glatfelter, Grant C

Toxicological evaluation, postmortem case descriptions, and pharmacological activity of N,N-dimethylpentylone and related analogs

N,N-二甲基戊酮及其类似物的毒理学评价、尸检案例描述和药理活性

Fogarty, Melissa F; Walton, Sara E; Truver, Michael T; Glatfelter, Grant C; Krotulski, Alex J; Papsun, Donna M; Lamb, Michael; Chronister, Chris W; Goldberger, Bruce A; Walther, Donna; Barba, Kristie; Baumann, Michael H; Logan, Barry K

Development and validation of an analytical method for the determination of select 4-position ring-substituted tryptamines in plasma by liquid chromatography-tandem mass spectrometry

利用液相色谱-串联质谱法测定血浆中特定4位环取代色胺的分析方法的建立与验证

Pego, Ana Miguel Fonseca; Schoffner, Malik; Sammeta, Vamshikrishna Reddy; Naeem, Marilyn; Manke, David R; Chadeayne, Andrew; Glatfelter, Grant C; Baumann, Michael H; Concheiro-Guisán, Marta

Rapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis

利用 DeepLabCut 和简易行为分析法对 C57BL/6J 小鼠的头部抽搐反应进行快速、开源和自动化的定量分析

Maitland, Alexander D; Gonzalez, Nicholas R; Walther, Donna; Pereira, Francisco; Baumann, Michael H; Glatfelter, Grant C

Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro µ-opioid receptor assays and in vivo behavioral studies in mice

新型硝嗪类娱乐性药物的特性分析:通过体外μ-阿片受体检测和小鼠体内行为学研究揭示其潜在风险

Vandeputte, Marthe M; Glatfelter, Grant C; Walther, Donna; Layle, Nathan K; St Germaine, Danielle M; Ujváry, István; Iula, Donna M; Baumann, Michael H; Stove, Christophe P

Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone

μ-阿片受体配体(S)-美沙酮具有独特的药效学特性和低滥用风险

Levinstein, Marjorie R; De Oliveira, Paulo A; Casajuana-Martin, Nil; Quiroz, Cesar; Budinich, Reece C; Rais, Rana; Rea, William; Ventriglia, Emilya N; Llopart, Natàlia; Casadó-Anguera, Verònica; Moreno, Estefanía; Walther, Donna; Glatfelter, Grant C; Weinshenker, David; Zarate, Carlos A Jr; Casadó, Vicent; Baumann, Michael H; Pardo, Leonardo; Ferré, Sergi; Michaelides, Michael