日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neuroglobin overexpression in cerebellar neurons of Harlequin mice improves mitochondrial homeostasis and reduces ataxic behavior

在哈莱昆小鼠的小脑神经元中过表达神经球蛋白可改善线粒体稳态并减少共济失调行为

Cwerman-Thibault, Hélène; Malko-Baverel, Vassilissa; Le Guilloux, Gwendoline; Ratcliffe, Edward; Mouri, Djmila; Torres-Cuevas, Isabel; Millán, Ivan; Saubaméa, Bruno; Mignon, Virginie; Boespflug-Tanguy, Odile; Gressens, Pierre; Corral-Debrinski, Marisol

A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development

对肿瘤临床药物研发中建模和仿真实践进行全面的监管和行业审查

Ruiz-Garcia, Ana; Baverel, Paul; Bottino, Dean; Dolton, Michael; Feng, Yan; González-García, Ignacio; Kim, Jaeyeon; Robey, Seth; Singh, Indrajeet; Turner, David; Wu, Shu-Pei; Yin, Donghua; Zhou, Di; Zhu, Hao; Bonate, Peter

Step-by-step comparison of ordinary differential equation and agent-based approaches to pharmacokinetic-pharmacodynamic models

逐步比较常微分方程法和基于代理的药代动力学-药效动力学模型方法

Truong, Van Thuy; Baverel, Paul G; Lythe, Grant D; Vicini, Paolo; Yates, James W T; Dubois, Vincent F S

Model enhanced reinforcement learning to enable precision dosing: A theoretical case study with dosing of propofol

利用模型增强强化学习实现精准给药:以丙泊酚给药为例的理论案例研究

Ribba, Benjamin; Bräm, Dominic Stefan; Baverel, Paul Gabriel; Peck, Richard Wilson

Exposure driven dose escalation design with overdose control: Concept and first real life experience in an oncology phase I trial

基于暴露量的剂量递增设计及过量控制:概念及在肿瘤学 I 期试验中的首次实际应用经验

Micallef, Sandrine; Sostelly, Alexandre; Zhu, Jiawen; Baverel, Paul G; Mercier, Francois

The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress

HSP GRP94 与巨噬细胞内补体 C3 相互作用,并在内质网应激期间影响 M2 表型。

Killian Chaumonnot ,Sophie Masson ,Hugo Sikner ,Alexanne Bouchard ,Valentin Baverel ,Pierre-Simon Bellaye ,Bertrand Collin ,Carmen Garrido ,Evelyne Kohli

Endoplasmic Reticulum Chaperones in Viral Infection: Therapeutic Perspectives

内质网分子伴侣在病毒感染中的作用:治疗前景

Kohli, Evelyne; Causse, Sébastien; Baverel, Valentin; Dubrez, Laurence; Borges-Bonan, Natalia; Demidov, Oleg; Garrido, Carmen

Association of circulating protein biomarkers with clinical outcomes of durvalumab in head and neck squamous cell carcinoma

循环蛋白生物标志物与度伐利尤单抗治疗头颈部鳞状细胞癌临床疗效的相关性

Arends, Rosalinda; Guo, Xiang; Baverel, Paul G; González-García, Ignacio; Xie, James; Morsli, Nassim; Yovine, Alejandro; Roskos, Lorin K

The GRP94 Inhibitor PU-WS13 Decreases M2-like Macrophages in Murine TNBC Tumors: A Pharmaco-Imaging Study with 99mTc-Tilmanocept SPECT

GRP94 抑制剂 PU-WS13 减少小鼠 TNBC 肿瘤中的 M2 样巨噬细胞:使用 99mTc-Tilmanocept SPECT 进行的药物成像研究

Alexanne Bouchard, Hugo Sikner, Valentin Baverel, Anaïs-Rachel Garnier, Marie Monterrat, Mathieu Moreau, Emeric Limagne, Carmen Garrido, Evelyne Kohli, Bertrand Collin, Pierre-Simon Bellaye

Pharmacokinetic-Pharmacodynamic Modelling of Systemic IL13 Blockade by Monoclonal Antibody Therapy: A Free Assay Disguised as Total

单克隆抗体疗法对全身 IL13 阻断的药代动力学-药效学建模:伪装成总

John Hood, Ignacio González-García, Nicholas White, Leeron Marshall, Vincent F S Dubois, Paolo Vicini, Paul G Baverel