Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.
合理优化药物靶点停留时间:从抑制剂与金黄色葡萄球菌 FabI 酶-产物复合物的结合中获得的启示
期刊:Biochemistry
影响因子:3
doi:10.1021/bi400413c
Chang Andrew, Schiebel Johannes, Yu Weixuan, Bommineni Gopal R, Pan Pan, Baxter Michael V, Khanna Avinash, Sotriffer Christoph A, Kisker Caroline, Tonge Peter J