日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Population Pharmacokinetics and Exposure-Response Analyses for Venetoclax in Combination with R-CHOP in Relapsed/Refractory and Previously Untreated Patients with Diffuse Large B Cell Lymphoma

维奈托克联合R-CHOP方案治疗复发/难治性及既往未接受治疗的弥漫性大B细胞淋巴瘤患者的群体药代动力学和暴露-反应分析

Samineni, Divya; Huang, Weize; Gibiansky, Leonid; Ding, Hao; Zhang, Rong; Li, Chunze; Sinha, Arijit; Rajwanshi, Richa; Humphrey, Kathryn; Bazeos, Alexandra; Salem, Ahmed Hamed; Miles, Dale

Prognostic mutational subtyping in de novo diffuse large B-cell lymphoma

新发弥漫性大B细胞淋巴瘤的预后突变亚型分析

Kim, Eugene; Jiang, Yanwen; Xu, Tao; Bazeos, Alexandra; Knapp, Andrea; Bolen, Christopher R; Humphrey, Kathryn; Nielsen, Tina G; Penuel, Elicia; Paulson, Joseph N

A phase 2 study of venetoclax plus R-CHOP as first-line treatment for patients with diffuse large B-cell lymphoma

一项评估维奈托克联合R-CHOP方案作为弥漫性大B细胞淋巴瘤患者一线治疗方案的II期研究

Morschhauser, Franck; Feugier, Pierre; Flinn, Ian W; Gasiorowski, Robin; Greil, Richard; Illés, Árpád; Johnson, Nathalie A; Larouche, Jean-François; Lugtenburg, Pieternella J; Patti, Caterina; Salles, Gilles A; Trněný, Marek; de Vos, Sven; Mir, Farheen; Samineni, Divya; Kim, Su Y; Jiang, Yanwen; Punnoose, Elizabeth; Sinha, Arijit; Clark, Emma; Spielewoy, Nathalie; Humphrey, Kathryn; Bazeos, Alexandra; Zelenetz, Andrew D

Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors

表观遗传修饰因子的体细胞变异可以预测对伊马替尼的反应失败,但不能预测对第二代酪氨酸激酶抑制剂的反应失败。

Nteliopoulos, Georgios; Bazeos, Alexandra; Claudiani, Simone; Gerrard, Gareth; Curry, Edward; Szydlo, Richard; Alikian, Mary; Foong, Hui En; Nikolakopoulou, Zacharoula; Loaiza, Sandra; Khorashad, Jamshid S; Milojkovic, Dragana; Perrotti, Danilo; Gale, Robert Peter; Foroni, Letizia; Apperley, Jane F

Current pre-clinical and clinical advances in the BCR-ABL1-positive and -negative chronic myeloproliferative neoplasms

BCR-ABL1阳性和阴性慢性骨髓增殖性肿瘤的临床前和临床进展

Mughal, Tariq I; Vannucchi, Alessandro M; Soverini, Simona; Bazeos, Alexandra; Tibes, Raoul; Saglio, Giuseppe; Abdel-Wahab, Omar; Pardanani, Animesh; Hehlmann, Rudiger; Barbui, Tiziano; Van Etten, Richard; Tefferi, Ayalew; Goldman, John M

Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling

酪氨酸激酶抑制剂通过脱靶抑制对细胞信号传导很重要的激酶,削弱 CML 中的 B 细胞免疫反应

Hugues de Lavallade, Ahmad Khoder, Melanie Hart, Anushruti Sarvaria, Takuya Sekine, Abdullah Alsuliman, Stephan Mielke, Alexandra Bazeos, Kate Stringaris, Sara Ali, Dragana Milojkovic, Letizia Foroni, Aristeidis Chaidos, Nichola Cooper, Ian Gabriel, Jane Apperley, Sarah Belsey, Robert J Flanagan, Jo

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

与血液相比,颊黏膜组织可能更适合作为表观基因组关联研究的替代组织。

Lowe, Robert; Gemma, Carolina; Beyan, Huriya; Hawa, Mohammed I; Bazeos, Alexandra; Leslie, R David; Montpetit, Alexandre; Rakyan, Vardhman K; Ramagopalan, Sreeram V

Biology of CML stem cells: the basis for clinical heterogeneity?

慢性粒细胞白血病干细胞的生物学特性:临床异质性的基础?

Goldman, J M; Gordon, M; Bazeos, A; Marin, D

Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib

对于接受伊马替尼治疗后达到完全细胞遗传学缓解的慢性粒细胞白血病患者而言,依从性是实现分子学缓解的关键因素。

Marin, David; Bazeos, Alexandra; Mahon, Francois-Xavier; Eliasson, Lina; Milojkovic, Dragana; Bua, Marco; Apperley, Jane F; Szydlo, Richard; Desai, Ritti; Kozlowski, Kasia; Paliompeis, Christos; Latham, Victoria; Foroni, Letizia; Molimard, Mathieu; Reid, Alistair; Rezvani, Katy; de Lavallade, Hugues; Guallar, Cristina; Goldman, John; Khorashad, Jamshid S