日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma

使用膦酸抑制剂C28靶向羧肽酶A/B活性可降低屋尘螨诱发哮喘小鼠模型的哮喘反应。

Allam, Venkata Sita Rama Raju; Montpeyó, David; Beau, Fabrice; Taha, Sowsan; Waern, Ida; Akula, Srinivas; Avilés, Francesc Xavier; Lorenzo, Julia; Devel, Laurent; Pejler, Gunnar; Wernersson, Sara

Covalent Labeling of Matrix Metalloproteases with Affinity-Based Probes Containing Tuned Reactive N-Acyl-N-Alkyl Sulfonamide Cleavable Linkers

利用含有可调控反应性N-酰基-N-烷基磺酰胺可裂解连接子的亲和探针,对基质金属蛋白酶进行共价标记

Devel, Laurent; Malgorn, Carole; Tohon, Regis-William; Launay, Marie; Patiniotis, Konstantinos; Sejalon-Cipolla, Mylene; Beau, Fabrice; Thai, Robert; Bruyat, Pierrick; Bonino, Annabelle; Bregant, Sarah; Subra, Gilles; Cantel, Sonia; Georgiadis, Dimitris

Monitoring In Vivo Performances of Protein-Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging

利用位点选择性双放射性标记和离体数字成像技术监测蛋白质-药物偶联物的体内性能

Cahuzac, Héloïse; Sallustrau, Antoine; Malgorn, Carole; Beau, Fabrice; Barbe, Peggy; Babin, Victor; Dubois, Steven; Palazzolo, Alberto; Thai, Robert; Correia, Isabelle; Lee, Ki Baek; Garcia-Argote, Sébastien; Lequin, Olivier; Keck, Mathilde; Nozach, Hervé; Feuillastre, Sophie; Ge, Xin; Pieters, Gregory; Audisio, Davide; Devel, Laurent

Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes

MMP-12选择性光学探针的合成、体外和体内评价

Bordenave, Thomas; Helle, Marion; Beau, Fabrice; Georgiadis, Dimitris; Tepshi, Livia; Bernes, Mylène; Ye, Yunpeng; Levenez, Laure; Poquet, Enora; Nozach, Hervé; Razavian, Mahmoud; Toczek, Jakub; Stura, Enrico A; Dive, Vincent; Sadeghi, Mehran M; Devel, Laurent

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme

高特异性膦酸三肽对映体与血管紧张素I转化酶复合物的晶体结构

Masuyer, Geoffrey; Akif, Mohd; Czarny, Bertrand; Beau, Fabrice; Schwager, Sylva L U; Sturrock, Edward D; Isaac, R Elwyn; Dive, Vincent; Acharya, K Ravi

A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice

选择性基质金属蛋白酶-12抑制剂可延缓载脂蛋白E敲除小鼠动脉粥样硬化斑块的形成

Johnson, Jason L; Devel, Laurent; Czarny, Bertrand; George, Sarah J; Jackson, Christopher L; Rogakos, Vassilis; Beau, Fabrice; Yiotakis, Athanasios; Newby, Andrew C; Dive, Vincent

Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide

一种高特异性膦酸三肽抑制人血管紧张素I转化酶(ACE)的新机制

Akif, Mohd; Schwager, Sylva L; Anthony, Colin S; Czarny, Bertrand; Beau, Fabrice; Dive, Vincent; Sturrock, Edward D; Acharya, K Ravi

Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.

从针对 MMP-12 的选择性非膦酸抑制剂中获得的见解,这些抑制剂经过专门设计以适应 S1' 环的典型构象

Devel Laurent, Garcia Sandra, Czarny Bertrand, Beau Fabrice, LaJeunesse Evelyne, Vera Laura, Georgiadis Dimitris, Stura Enrico, Dive Vincent