日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo

横纹肌肉瘤的新型小鼠模型强调了体内 MDM2-ALT1 功能的二分性

D F Comiskey Jr, A G Jacob, B L Sanford, M Montes, A K Goodwin, H Steiner, E Matsa, A S Tapia-Santos, T W Bebee, J Grieves, K La Perle, P Boyaka, D S Chandler

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development

ESRP1 突变导致听力损失,这是由于选择性剪接缺陷破坏了耳蜗发育

Alex M Rohacek, Thomas W Bebee, Richard K Tilton, Caleb M Radens, Chris McDermott-Roe, Natoya Peart, Maninder Kaur, Michael Zaykaner, Benjamin Cieply, Kiran Musunuru, Yoseph Barash, John A Germiller, Ian D Krantz, Russ P Carstens, Douglas J Epstein

Determination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal Transition

上皮-间质转化过程中综合剪接调控网络的确定及关键因子的组合调控

Yueqin Yang, Juw Won Park, Thomas W Bebee, Claude C Warzecha, Yang Guo, Xuequn Shang, Yi Xing, Russ P Carstens

Ablation of the epithelial-specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number.

上皮特异性剪接因子 Esrp1 的缺失会导致输尿管分支缺陷和肾单位数量减少

Bebee Thomas W, Sims-Lucas Sunder, Park Juw Won, Bushnell Daniel, Cieply Benjamin, Xing Yi, Bates Carlton M, Carstens Russ P

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation

ESRP2 控制肝细胞中的成体剪接程序,以支持出生后肝脏成熟

Amruta Bhate, Darren J Parker, Thomas W Bebee, Jaegyoon Ahn, Waqar Arif, Edrees H Rashan, Sandip Chorghade, Anthony Chau, Jae-Hyung Lee, Sayeepriyadarshini Anakk, Russ P Carstens, Xinshu Xiao, Auinash Kalsotra

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development

剪接调节因子Esrp1和Esrp2指导着上皮细胞剪接程序,该程序对哺乳动物发育至关重要。

Bebee, Thomas W; Park, Juw Won; Sheridan, Katherine I; Warzecha, Claude C; Cieply, Benjamin W; Rohacek, Alex M; Xing, Yi; Carstens, Russ P

The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA

剪接因子 FUBP1 是致癌基因 MDM2 前 mRNA 有效剪接所必需的

Aishwarya G Jacob, Ravi K Singh, Fuad Mohammad, Thomas W Bebee, Dawn S Chandler

Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways

应激诱导的 MDM2 和 MDMX 替代剪接形式以不同的方式调节 p53 通路

Aishwarya G Jacob, Ravi K Singh, Daniel F Comiskey Jr, Matthew F Rouhier, Fuad Mohammad, Thomas W Bebee, Dawn S Chandler

Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model

在重症SMA小鼠模型中,缺氧会影响SMN2剪接和疾病严重程度。

Bebee, Thomas W; Dominguez, Catherine E; Samadzadeh-Tarighat, Somayeh; Akehurst, Kristi L; Chandler, Dawn S

Generation of a tamoxifen inducible SMN mouse for temporal SMN replacement

构建他莫昔芬诱导型SMN小鼠模型用于SMN的暂时性替代疗法

Bebee, Thomas W; Gladman, Jordan T; Chandler, Dawn S