Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis
一项针对ACPA阳性类风湿性关节炎患者的随机I期临床试验,研究肽/骨化三醇脂质体抗原特异性耐受免疫疗法的疗效
期刊:JCI Insight
影响因子:6.3
doi:10.1172/jci.insight.160964.
Amee Sonigra ,Hendrik J Nel ,Pascale Wehr ,Nishta Ramnoruth ,Swati Patel ,Karin A van Schie ,Maxwell W Bladen ,Ahmed M Mehdi ,Joanne Tesiram ,Meghna Talekar ,Jamie Rossjohn ,Hugh H Reid ,Frederik E Stuurman ,Helen Roberts ,Phillip Vecchio ,Ian Gourley ,Mark Rigby ,Stephane Becart ,Rene Em Toes ,Hans Ulrich Scherer ,Kim-Anh Lê Cao ,Kim Campbell ,Ranjeny Thomas