Becker Howard C相关文献与解析，生知库 | 链接生命科学的每一步

Edvardsson, Christian E; Adermark, Louise; Gottlieb, Sam; Alfreji, Safana; Emous, Thaynnam A; Gouda, Yomna; Thorsell, Annika; Vujičić, Milica; Aranäs, Cajsa; Benrick, Anna; Wernstedt Asterholm, Ingrid; Lopez, Marcelo F; Becker, Howard C; Jerlhag, Elisabet

发表日期：2026

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Mediodorsal thalamus of alcohol-dependent mice shows genetic and physiological adaptations and alcohol-biased calcium signaling

酒精依赖小鼠的丘脑背内侧核表现出遗传和生理适应性以及酒精偏向性钙信号传导

期刊:Neuropharmacology

影响因子:4.6

doi:10.1016/j.neuropharm.2026.110883

Martin, Jayden C; Reeves, Kaitlin C; Carter, Kathryn A; Davis, Matthew; Schneider, Amelia; Meade, Elizabeth; Lebonville, Christina L; Nimitvilai-Roberts, Sudarat; Hoffman, Michaela; Woodward, John J; Loewinger, Gabriel; Smith, Rachel J; Lopez, Marcelo F; Becker, Howard C; Mulholland, Patrick J; Rinker, Jennifer A

G9a inhibition reduces stress-potentiated alcohol drinking in both male and female mice: Implications for safe and effective pharmacological therapeutics for alcohol use disorder

G9a抑制剂可降低雄性和雌性小鼠应激增强的饮酒行为：对安全有效的酒精使用障碍药物治疗的启示

期刊:ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

影响因子:3

doi:10.1111/acer.70277

Holmes, Deltrice; Lopez, Marcelo F; Becker, Howard C; Cowan, Christopher W; Anderson, Ethan M

发表日期：2026

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Engaging Gut-to-Brain Signalling to Treat Alcohol Use Disorder

利用肠脑信号通路治疗酒精使用障碍

期刊:Addiction Biology

影响因子:2.6

doi:10.1111/adb.70144

Hoffman, Paula L; de Guglielmo, Giordano; Vengeliene, Valentina; Kunze, Wolfgang; Lebonville, Christina L; Swinny, Jerome D; Roberts, Amanda J; George, Olivier; Neufeld, Karen-Anne McVey; Dunbar, Alexandra; Saba, Laura M; Ma, Ruolin; Vendruscolo, Leandro F; Becker, Howard C; Spanagel, Rainer; Tabakoff, Boris

Translating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis

利用荟萃分析方法，将药物对酒精使用障碍的疗效从临床前研究、人体实验室研究和临床试验结果中进行转化

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-025-03473-6

Nieto, Steven J; Donato, Suzanna; Du, Han; Meredith, Lindsay R; Baskerville, Wave-Ananda; McManus, Kaitlin R; Magill, Molly; Lopez, Marcelo F; Becker, Howard C; Ray, Lara A

发表日期：2025

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Alcohol drinking is associated with greater calcium activity in mouse central amygdala dynorphin-expressing neurons

饮酒与小鼠中央杏仁核强啡肽表达神经元中钙活性增强有关。

期刊:Progress in Neuro-Psychopharmacology & Biological Psychiatry

影响因子:3.9

doi:10.1016/j.pnpbp.2025.111445

Lebonville, Christina L; Rinker, Jennifer A; O'Hara, Krysten; McMahan, Christopher S; Hoffman, Michaela; Becker, Howard C; Mulholland, Patrick J

神经科学

发表日期：2025

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Targeting G9a decreases escalated alcohol drinking in male mice in a model of combined stress and chronic alcohol exposure

在同时受到应激和慢性酒精暴露的小鼠模型中，靶向 G9a 可降低雄性小鼠的饮酒量。

期刊:ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

影响因子:3

doi:10.1111/acer.70142

Lopez, Marcelo F; Misztak, Paulina; Becker, Howard C; Cowan, Christopher W; Anderson, Ethan M

发表日期：2025

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Cyp2e1 deletion in mice increases sensitivity to ethanol-induced motor impairment and escalation of drinking behavior in the chronic intermittent ethanol model

小鼠Cyp2e1基因缺失会增加慢性间歇性乙醇模型中小鼠对乙醇诱导的运动障碍的敏感性，并加剧饮酒行为。

期刊:ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

影响因子:3

doi:10.1111/acer.70188

Gonzalez, Hyland C; Misare, Kelly R; Glorioso, Kate E; Delaney, Joe R; Becker, Howard C; Lopez, Marcelo F; Mulholland, Patrick J; Hartman, Jessica H

发表日期：2025

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Transcriptome changes in the nucleus of the solitary tract induced by repeated stress, alcohol dependence, or stress-induced drinking in dependent mice

重复应激、酒精依赖或依赖小鼠应激诱导饮酒引起的孤束核转录组变化

期刊:Neuropharmacology

影响因子:4.6

doi:10.1016/j.neuropharm.2023.109768

Grantham, Emily K; Tiwari, Gayatri R; Ponomareva, Olga; Harris, R Adron; Lopez, Marcello F; Becker, Howard C; Mayfield, R Dayne

发表日期：2024

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Preclinical and clinical evidence for suppression of alcohol intake by apremilast

阿普米司特抑制酒精摄入的临床前和临床证据

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI159103

Grigsby, Kolter B; Mangieri, Regina A; Roberts, Amanda J; Lopez, Marcelo F; Firsick, Evan J; Townsley, Kayla G; Beneze, Alan; Bess, Jessica; Eisenstein, Toby K; Meissler, Joseph J; Light, John M; Miller, Jenny; Quello, Susan; Shadan, Farhad; Skinner, Michael; Aziz, Heather C; Metten, Pamela; Morrisett, Richard A; Crabbe, John C; Roberto, Marisa; Becker, Howard C; Mason, Barbara J; Ozburn, Angela R

发表日期：2023

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Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents

替拉帕肽可减少啮齿动物的饮酒量和复发样行为

Mediodorsal thalamus of alcohol-dependent mice shows genetic and physiological adaptations and alcohol-biased calcium signaling

酒精依赖小鼠的丘脑背内侧核表现出遗传和生理适应性以及酒精偏向性钙信号传导

G9a inhibition reduces stress-potentiated alcohol drinking in both male and female mice: Implications for safe and effective pharmacological therapeutics for alcohol use disorder

G9a抑制剂可降低雄性和雌性小鼠应激增强的饮酒行为：对安全有效的酒精使用障碍药物治疗的启示

Engaging Gut-to-Brain Signalling to Treat Alcohol Use Disorder

利用肠脑信号通路治疗酒精使用障碍

Translating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis

利用荟萃分析方法，将药物对酒精使用障碍的疗效从临床前研究、人体实验室研究和临床试验结果中进行转化

Alcohol drinking is associated with greater calcium activity in mouse central amygdala dynorphin-expressing neurons

饮酒与小鼠中央杏仁核强啡肽表达神经元中钙活性增强有关。

Targeting G9a decreases escalated alcohol drinking in male mice in a model of combined stress and chronic alcohol exposure

在同时受到应激和慢性酒精暴露的小鼠模型中，靶向 G9a 可降低雄性小鼠的饮酒量。

Cyp2e1 deletion in mice increases sensitivity to ethanol-induced motor impairment and escalation of drinking behavior in the chronic intermittent ethanol model

小鼠Cyp2e1基因缺失会增加慢性间歇性乙醇模型中小鼠对乙醇诱导的运动障碍的敏感性，并加剧饮酒行为。

Transcriptome changes in the nucleus of the solitary tract induced by repeated stress, alcohol dependence, or stress-induced drinking in dependent mice

重复应激、酒精依赖或依赖小鼠应激诱导饮酒引起的孤束核转录组变化

Preclinical and clinical evidence for suppression of alcohol intake by apremilast

阿普米司特抑制酒精摄入的临床前和临床证据