日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Production and characterization of rNGFSP: a recombinant fusion immunogen eliciting dual anti-NGF and anti-Substance P therapeutic antibodies for Degenerative Joint Disease.

rNGFSP 的生产和表征：一种重组融合免疫原，可诱导产生用于治疗退行性关节疾病的双重抗 NGF 和抗 P 物质治疗性抗体。

期刊:Biotechnology Reports
影响因子:
doi:10.1016/j.btre.2026.e00946
Varela Valentina, Costa Monique, Maciel Cecilia, Barbeito Joaquín, Barrera Exequiel E, Gutierre Erica, Correa Agustín, Elgue Melania, Carrasco Sebastián, Larrosa Magdalena Domínguez, Pereira María, Correa Josefina, Crosignani Nadia, Beckman Joseph S, Barbeito Luis, Trias Emiliano
免疫/内分泌
NGF
发表日期：2026
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The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-implications for the toxic gain of function observed in ALS

异二聚体锌缺乏型SOD1的结构、氧化还原化学性质及其对运动神经元的毒性——对ALS中观察到的毒性功能获得的意义

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2025.107189
Streltsov, Victor A; Ganio, Katherine E; Nuttall, Stewart D; Hernandez, J Andres; Dennys, Cassandra N; Crouch, Peter J; Estevez, Alvaro G; Franco, Maria Clara; Beckman, Joseph S; Roberts, Blaine R
SOD1
毒理研究
神经科学
ALS
发表日期：2025
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Electron Capture Dissociation for Discovery Top-Down Proteomics of Peptides and Small Proteins on Chromatographic Time Scales

电子捕获解离技术在色谱时间尺度上对肽和小蛋白进行自上而下的蛋白质组学发现

期刊:Journal of the American Society for Mass Spectrometry
影响因子:2.7
doi:10.1021/jasms.5c00116
Manly, Lester S; Roberts, Anne M; Beckman, Joseph S; Roberts, Blaine R
发表日期：2025
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The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-Implications for the toxic gain of function observed in ALS

异二聚体锌缺乏型SOD1的结构、氧化还原化学性质及其对运动神经元的毒性——对ALS中观察到的毒性功能获得性的启示

期刊:
影响因子:
doi:10.1101/2025.09.10.675162
Streltsov, Victor A; Ganio, Katherine E; Nuttall, Stewart D; Hernandez, J Andres; Dennys, Cassandra N; Crouch, Peter J; Estevez, Alvaro G; Franco, Maria Clara; Beckman, Joseph S; Roberts, Blaine R
SOD1
毒理研究
神经科学
ALS
发表日期：2025
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Capillary Zone Electrophoresis-Electron-Capture Collision-Induced Dissociation on a Quadrupole Time-of-Flight Mass Spectrometer for Top-Down Characterization of Intact Proteins

毛细管区带电泳-电子捕获碰撞诱导解离-四极杆飞行时间质谱法用于完整蛋白质的自上而下表征

期刊:Journal of the American Society for Mass Spectrometry
影响因子:2.7
doi:10.1021/jasms.0c00484
Shen, Xiaojing; Xu, Tian; Hakkila, Blake; Hare, Mike; Wang, Qianjie; Wang, Qianyi; Beckman, Joseph S; Sun, Liangliang
发表日期：2021
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Direct Determination of Antibody Chain Pairing by Top-down and Middle-down Mass Spectrometry Using Electron Capture Dissociation and Ultraviolet Photodissociation

利用电子捕获解离和紫外光解离的自上而下和自中而下的质谱法直接测定抗体链配对

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.9b03129
Shaw, Jared B; Liu, Weijing; Vasil Ev, Yury V; Bracken, Carter C; Malhan, Neha; Guthals, Adrian; Beckman, Joseph S; Voinov, Valery G
发表日期：2020
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Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer.

利用改进的离子迁移质谱仪中的电子捕获解离技术，对变性蛋白质和天然蛋白质复合物进行自上而下的表征

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.9b04763
Williams Jonathan P, Morrison Lindsay J, Brown Jeffery M, Beckman Joseph S, Voinov Valery G, Lermyte Frederik
其它
发表日期：2020
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Cu(II)(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord

Cu(II)(atsm)可改善SOD1(G93A)小鼠的神经表型和存活率，并选择性地增加脊髓中具有酶活性的SOD1。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep42292
Hilton, James B; Mercer, Stephen W; Lim, Nastasia K H; Faux, Noel G; Buncic, Gojko; Beckman, Joseph S; Roberts, Blaine R; Donnelly, Paul S; White, Anthony R; Crouch, Peter J
SOD1
神经科学
发表日期：2017
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Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

麻痹后使用马西替尼抑制酪氨酸激酶可消除神经炎症并延缓遗传性肌萎缩侧索硬化症的疾病进展

期刊:Journal of Neuroinflammation
影响因子:10.1
doi:10.1186/s12974-016-0620-9
Trias, Emiliano; Ibarburu, Sofía; Barreto-Núñez, Romina; Babdor, Joël; Maciel, Thiago T; Guillo, Matthias; Gros, Laurent; Dubreuil, Patrice; Díaz-Amarilla, Pablo; Cassina, Patricia; Martínez-Palma, Laura; Moura, Ivan C; Beckman, Joseph S; Hermine, Olivier; Barbeito, Luis
炎症
炎症/感染
信号转导
神经科学
神经炎症
发表日期：2016
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Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.

CuATSM 将铜输送到中枢神经系统可有效治疗共表达 SOD 铜伴侣蛋白的 SOD(G93A) 小鼠的运动神经元疾病

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2016.01.020
Williams Jared R, Trias Emiliano, Beilby Pamela R, Lopez Nathan I, Labut Edwin M, Bradford C Samuel, Roberts Blaine R, McAllum Erin J, Crouch Peter J, Rhoads Timothy W, Pereira Cliff, Son Marjatta, Elliott Jeffrey L, Franco Maria Clara, Estévez Alvaro G, Barbeito Luis, Beckman Joseph S
神经科学
发表日期：2016
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