Begley Thomas J相关文献与解析，生知库 | 链接生命科学的每一步

Lysosomal Profiling with LysoTracker for Quantitative Assessment of Cellular Senescence in Human Fibroblasts

利用LysoTracker进行溶酶体谱分析以定量评估人类成纤维细胞的细胞衰老

期刊:

影响因子:

doi:10.64898/2026.04.16.719007

Estrada, Javier; Tenenbaum, Scott; Larsen, Melinda; Begley, Thomas J; Melendez, J A

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa

tRNA修饰谱分析揭示铜绿假单胞菌的表观转录组调控网络

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf696

Sun, Jingjing; Wu, Junzhou; Yuan, Yifeng; Fan, Leon; Chua, Wei Lin Patrina; Ling, Yan Han Sharon; Balamkundu, Seetharamsing; Dwijapriya; Chay, Hazel Suen Suen; Begley, Thomas J; de Crécy-Lagard, Valérie; Dziergowska, Agnieszka; Dedon, Peter C

A Geranylated Natural Product Simamycin Disrupts the Allosteric Catalysis of tRNA-2-selenouridine Synthase SelU

一种香叶基化的天然产物西玛霉素可干扰tRNA-2-硒尿苷合成酶SelU的变构催化。

期刊:Biochemistry

影响因子:3

doi:10.1021/acs.biochem.5c00053

Dansereau, Stephen J; Shekhtman, Alexander; Epifano, Francesco; Genovese, Salvatore; Fiorito, Serena; Begley, Thomas J; Sheng, Jia

发表日期：2025

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Loss of the s (2) U tRNA modification induces antibiotic tolerance and is linked to changes in ribosomal protein expression

s(2)U tRNA修饰的缺失会诱导抗生素耐药性，并与核糖体蛋白表达的变化有关。

期刊:

影响因子:

doi:10.1101/2025.07.01.662621

Cotten, Katherine L; McShane, Abigail; Dedon, Peter C; Begley, Thomas J; Davis, Kimberly M

发表日期：2025

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Genes and Pathways Comprising the Human and Mouse ORFeomes Display Distinct Codon Bias Signatures that Can Regulate Protein Levels

人类和小鼠开放阅读框组的基因和通路表现出独特的密码子偏好特征，这些特征可以调节蛋白质水平。

期刊:

影响因子:

doi:10.1101/2025.02.03.636209

Davis, Evan T; Raman, Rahul; Byrne, Shane R; Ghanegolmohammadi, Farzan; Mathur, Chetna; Begley, Ulrike; Dedon, Peter C; Begley, Thomas J

Correction to "Molecular Coping Mechanisms: Reprogramming tRNAs to Regulate Codon-Biased Translation of Stress Response Proteins"

对“分子应对机制：重编程 tRNA 以调节应激反应蛋白的密码子偏向性翻译”的更正

期刊:Accounts of Chemical Research

影响因子:17.7

doi:10.1021/acs.accounts.4c00466

Mitchener, Michelle M; Begley, Thomas J; Dedon, Peter C

发表日期：2024

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Stress response regulation of mRNA translation: Implications for antioxidant enzyme expression in cancer

应激反应调控mRNA翻译：对癌症中抗氧化酶表达的影响

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2317846121

Kim, Yeon Soo; Kimball, Scot R; Piskounova, Elena; Begley, Thomas J; Hempel, Nadine

ROS-induced translational regulation-through spatiotemporal differences in codon recognition-is a key driver of brown adipogenesis

ROS诱导的翻译调控——通过密码子识别的时空差异——是棕色脂肪生成的关键驱动因素。

期刊:

影响因子:

doi:10.1101/2023.12.22.572954

Ip, Jun Yu; Wijaya, Indrik; Lee, Li Ting; Lim, Yuhua; Teoh, Deryn En-Jie; Chan, Cheryl Siew Choo; Cui, Liang; Begley, Thomas J; Dedon, Peter C; Guo, Huili

Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins

分子应对机制：重编程tRNA以调节应激反应蛋白的密码子偏向性翻译

期刊:Accounts of Chemical Research

影响因子:17.7

doi:10.1021/acs.accounts.3c00572

Mitchener, Michelle M; Begley, Thomas J; Dedon, Peter C

发表日期：2023

文献求助收藏

Synonymous codon usage defines functional gene families

同义密码子的使用定义了功能基因家族

Lysosomal Profiling with LysoTracker for Quantitative Assessment of Cellular Senescence in Human Fibroblasts

利用LysoTracker进行溶酶体谱分析以定量评估人类成纤维细胞的细胞衰老

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa

tRNA修饰谱分析揭示铜绿假单胞菌的表观转录组调控网络

A Geranylated Natural Product Simamycin Disrupts the Allosteric Catalysis of tRNA-2-selenouridine Synthase SelU

一种香叶基化的天然产物西玛霉素可干扰tRNA-2-硒尿苷合成酶SelU的变构催化。

Loss of the s (2) U tRNA modification induces antibiotic tolerance and is linked to changes in ribosomal protein expression

s(2)U tRNA修饰的缺失会诱导抗生素耐药性，并与核糖体蛋白表达的变化有关。

Genes and Pathways Comprising the Human and Mouse ORFeomes Display Distinct Codon Bias Signatures that Can Regulate Protein Levels

人类和小鼠开放阅读框组的基因和通路表现出独特的密码子偏好特征，这些特征可以调节蛋白质水平。

Correction to "Molecular Coping Mechanisms: Reprogramming tRNAs to Regulate Codon-Biased Translation of Stress Response Proteins"

对“分子应对机制：重编程 tRNA 以调节应激反应蛋白的密码子偏向性翻译”的更正

Stress response regulation of mRNA translation: Implications for antioxidant enzyme expression in cancer

应激反应调控mRNA翻译：对癌症中抗氧化酶表达的影响

ROS-induced translational regulation-through spatiotemporal differences in codon recognition-is a key driver of brown adipogenesis

ROS诱导的翻译调控——通过密码子识别的时空差异——是棕色脂肪生成的关键驱动因素。

Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins

分子应对机制：重编程tRNA以调节应激反应蛋白的密码子偏向性翻译