日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage

选择性敲除反应性星形胶质细胞中的NBCe1可减轻缺血性中风造成的脑损伤

Capuk, Okan; Berthold, Elise; Kaliyappan, Kathiravan; Avunoori, Mansi; Muduganti, Rajesh; Krishna, Sanjana; Metwally, Shamseldin; McFarland, Mary; Song, Shanshan; Fiesler, Victoria; Fischer, Sydney; Foley, Lesley M; Hitchens, T Kevin; Waxman, Susannah; Sigal, Ian A; Theparambil, Shefeeq M; Begum, Gulnaz

Dysregulation of Ion Channels and Transporters and Blood-Brain Barrier Dysfunction in Alzheimer's Disease and Vascular Dementia

阿尔茨海默病和血管性痴呆中离子通道和转运蛋白的失调以及血脑屏障功能障碍

Liu, Ruijia; Collier, Jenelle M; Abdul-Rahman, Nana-Hawwa; Capuk, Okan; Zhang, Zhongling; Begum, Gulnaz

pH regulating mechanisms of astrocytes: A critical component in physiology and disease of the brain

星形胶质细胞的pH调节机制:大脑生理和疾病的关键组成部分

Theparambil, Shefeeq M; Begum, Gulnaz; Rose, Christine R

NOX activation in reactive astrocytes regulates astrocytic LCN2 expression and neurodegeneration

反应性星形胶质细胞中NOX的激活调节星形胶质细胞LCN2的表达和神经退行性变。

Liu, Ruijia; Wang, Jun; Chen, Yang; Collier, Jenelle M; Capuk, Okan; Jin, Shijie; Sun, Ming; Mondal, Sujan K; Whiteside, Theresa L; Stolz, Donna B; Yang, Yongjie; Begum, Gulnaz

Blockade of Cell Volume Regulatory Protein NKCC1 Increases TMZ-Induced Glioma Apoptosis and Reduces Astrogliosis.

阻断细胞体积调节蛋白 NKCC1 可增加 TMZ 诱导的胶质瘤细胞凋亡并减少星形胶质增生

Luo Lanxin, Guan Xiudong, Begum Gulnaz, Ding Dawei, Gayden Jenesis, Hasan Md Nabiul, Fiesler Victoria M, Dodelson Jacob, Kohanbash Gary, Hu Baoli, Amankulor Nduka M, Jia Wang, Castro Maria G, Sun Baoshan, Sun Dandan

Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy

阻断钠/氢交换器可刺激胶质瘤的免疫原性,并增强替莫唑胺和抗PD-1联合疗法的疗效。

Guan, Xiudong; Hasan, Md Nabiul; Begum, Gulnaz; Kohanbash, Gary; Carney, Karen E; Pigott, Victoria M; Persson, Anders I; Castro, Maria G; Jia, Wang; Sun, Dandan

Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke

小鼠体内WNK3-SPAK激酶复合物的缺失可改善缺血性卒中后恶性脑水肿的影像学和临床预后。

Zhao, Hanshu; Nepomuceno, Rachel; Gao, Xin; Foley, Lesley M; Wang, Shaoxia; Begum, Gulnaz; Zhu, Wen; Pigott, Victoria M; Falgoust, Lindsay M; Kahle, Kristopher T; Yang, Sung-Sen; Lin, Shih-Hua; Alper, Seth L; Hitchens, T Kevin; Hu, Shaoshan; Zhang, Zhongling; Sun, Dandan

Glial Na(+) -dependent ion transporters in pathophysiological conditions

病理生理状态下神经胶质细胞钠离子依赖性离子转运体

Boscia, Francesca; Begum, Gulnaz; Pignataro, Giuseppe; Sirabella, Rossana; Cuomo, Ornella; Casamassa, Antonella; Sun, Dandan; Annunziato, Lucio

Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain.

功能性激酶组学确定了哺乳动物大脑中体积敏感阳离子-Cl(-)共转运蛋白调节的关键节点

Zhang Jinwei, Gao Geng, Begum Gulnaz, Wang Jinhua, Khanna Arjun R, Shmukler Boris E, Daubner Gerrit M, de Los Heros Paola, Davies Paul, Varghese Joby, Bhuiyan Mohammad Iqbal H, Duan Jinjing, Zhang Jin, Duran Daniel, Alper Seth L, Sun Dandan, Elledge Stephen J, Alessi Dario R, Kahle Kristopher T

Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing.

利用 CRISPR/Cas 介导的基因组编辑技术构建 WNK1 基因敲除细胞系

Roy Ankita, Goodman Joshua H, Begum Gulnaz, Donnelly Bridget F, Pittman Gabrielle, Weinman Edward J, Sun Dandan, Subramanya Arohan R