日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy, safety, pharmacokinetics, and associated microbiome changes of ibezapolstat compared with vancomycin in adults with Clostridioides difficile infection: a phase 2b, randomised, double-blind, active-controlled, multicentre study

伊贝扎泊司他与万古霉素治疗成人艰难梭菌感染的疗效、安全性、药代动力学及相关微生物组变化:一项2b期随机、双盲、阳性对照、多中心研究

Eubank, Taryn A; Jo, Jinhee; Alam, M Jahangir; Begum, Khurshida; McPherson, Jacob K; Le, ThanhPhuong M; Horvath, Thomas D; Haidacher, Sigmund J; Poggio, Eugene C; Lin, Rong; Yue, Corinne Seng; Ducharme, Murray P; Koudssi, Georges; Mercier, Julie; Alder, Jeffrey D; Silverman, Michael H; Garey, Kevin W

Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin

一项比较接受奥马环素或万古霉素治疗的人类受试者粪便中胆汁酸和短链脂肪酸变化的I期临床试验

Jo, Jinhee; Hu, Chenlin; Horvath, Thomas D; Haidacher, Sigmund J; Begum, Khurshida; Alam, M Jahangir; Garey, Kevin W

P-221. Ribotype Ecology and 90-day Mortality Changes after a CDI Diagnostic Change from a PCR-based to a 2-step Diagnostic Algorithm

P-221. 艰难梭菌感染诊断方法从基于PCR的诊断算法转变为两步诊断算法后,核糖体分型生态学和90天死亡率的变化

Smalla, Kornelia; Jechalke, Sven; Top, Eva M; Huynh-Phan, Ricky; Eubank, Taryn A; Le, Thanh; Gonzales-Luna, Anne J; Jo, Jinhee; Begum, Khurshida; Alam, M Jahangir; Lasco, Todd M; Al Mohajer, Mayar; Garey, Kevin W

Faecal pharmacokinetics, microbiome, and bile acid changes in healthy subjects given intravenous followed by oral omadacycline; a Phase 1 clinical trial

健康受试者静脉注射奥马环素后口服奥马环素,其粪便药代动力学、微生物组和胆汁酸变化:一项 I 期临床试验

Jo, Jinhee; Carlson, Travis J; Hu, Chenlin; Williamson, John C; Belin, Yolanda T; Horvath, Thomas D; Haidacher, Sigmund J; Bassères, Eugénie; Begum, Khurshida; Alam, M Jahangir; Garey, Kevin W

Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile

伊贝扎波尔司他针对耐药性艰难梭菌临床菌株的抗菌活性

Bassères, Eugénie; Eubank, Taryn A; Begum, Khurshida; Alam, M Jahangir; Jo, Jinhee; Le, Thanh M; Lancaster, Chris K; Gonzales-Luna, Anne J; Garey, Kevin W

Comparison of Risk Stratification Approaches to Identify Patients with Clostridioides difficile Infection at Risk for Multidrug-Resistant Organism Gut Microbiota Colonization

比较风险分层方法以识别有多重耐药菌肠道菌群定植风险的艰难梭菌感染患者

Zasowski, Evan J; Ali, Maryam; Anugo, Ada; Ibragimova, Nayle; Dotson, Kierra M; Endres, Bradley T; Begum, Khurshida; Alam, M Jahangir; Garey, Kevin W

Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London

孟加拉国和伦敦的孟加拉裔人群中年时期植物雌激素摄入频率及相关症状

Sievert, Lynnette Leidy; Sharmeen, Taniya; Begum, Khurshida; Muttukrishna, Shanthi; Chowdhury, Osul; Bentley, Gillian R

Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants

童年环境影响英国-孟加拉移民中CpG时钟位点的表观遗传年龄和甲基化一致性

Stöger, Reinhard; Choi, Minseung; Begum, Khurshida; Leeman, Gregory; Emes, Richard D; Melamed, Philippa; Bentley, Gillian R

Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial

伊贝扎泊司他治疗成人艰难梭菌感染的疗效、安全性、药代动力学和微生物组变化:一项 2a 期多中心临床试验

Garey, Kevin W; McPherson, Jacob; Dinh, An Q; Hu, Chenlin; Jo, Jinhee; Wang, Weiqun; Lancaster, Chris K; Gonzales-Luna, Anne J; Loveall, Caroline; Begum, Khurshida; Jahangir Alam, M; Silverman, Michael H; Hanson, Blake M

Functional and Metagenomic Evaluation of Ibezapolstat for Early Evaluation of Anti-Recurrence Effects in Clostridioides difficile Infection

伊贝扎泊司他用于早期评估其在艰难梭菌感染中抗复发作用的功能和宏基因组学评价

McPherson, Jacob; Hu, Chenlin; Begum, Khurshida; Wang, Weiqun; Lancaster, Chris; Gonzales-Luna, Anne J; Loveall, Caroline; Silverman, Michael H; Alam, M Jahangir; Garey, Kevin W