日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Potassium-chloride cotransporter 2 activity dampens induced ictal-like activity in neocortical slices containing the seizure propagation zone of temporal lobe epilepsy patients

钾-氯共转运蛋白2活性可抑制颞叶癫痫患者新皮质切片(包含癫痫发作传播区)中诱发的癫痫样活动

Falck, Alice; Lehnhoff, Janna; Behbood, Mahraz; Byvaltcev, Egor; Aigner, Annette; Radbruch, Helena; Fidzinski, Pawel; Schleimer, Jan-Hendrik; Janach, Gabriel M S; Döhne, Noah; Onken, Julia; Kalbhenn, Thilo; Sauvigny, Thomas; Deisz, Rudolf A; Schreiber, Susanne; Holtkamp, Martin; Strauss, Ulf

Absorption, Metabolism, Distribution and Excretion (ADME) and Absolute Bioavailability Assessment of Zongertinib in Healthy Male Volunteers

宗格替尼在健康男性志愿者中的吸收、代谢、分布和排泄(ADME)及绝对生物利用度评估

Grempler, Rolf; Joseph, David; Gan, Guanfa; Auclair, Adam M; Tiessen, Renger G; Maw, Hlaing H; Laux, Ralf; Wind, Sven; Roessner, Philipp M; Sadrolhefazi, Behbood; Müller, Fabian; Minich, David

HER2-Selective Tyrosine Kinase Inhibitor, Zongertinib (BI 1810631), in Patients With Advanced/Metastatic Solid Tumors With HER2 Alterations: A Phase Ia Dose-Escalation Study

HER2选择性酪氨酸激酶抑制剂Zongertinib(BI 1810631)治疗HER2改变的晚期/转移性实体瘤患者:一项Ia期剂量递增研究

Heymach, John V; Opdam, Frans; Barve, Minal; Tu, Hai-Yan; Wu, Yi-Long; Berz, David; Schröter, Lukas; Botilde, Yanick; Sadrolhefazi, Behbood; Serra, Josep; Yoh, Kiyotaka; Yamamoto, Noboru

Nonclinical and Clinical Assessments of an Optimized Tablet Formulation of the Novel HER2-Selective Tyrosine Kinase Inhibitor Zongertinib: Focus on Relative Bioavailability and Impact of Variation of Gastric pH

新型HER2选择性酪氨酸激酶抑制剂Zongertinib优化片剂制剂的非临床和临床评估:重点关注相对生物利用度和胃pH值变化的影响

Wölke, Stefan; Sadrolhefazi, Behbood; Esmaeili, Habib; Wind, Sven; Blattner, Simone M; Gan, Guanfa; Qiang, Dongmei; Schirmer, Andrea; Müller, Fabian

Relative Bioavailability of Zongertinib, an Orally Administered HER2-Selective Tyrosine Kinase Inhibitor, under Fed and Fasted Conditions in Healthy Male Participants: Results from Two Randomized, Open-Label, Crossover Studies

在健康男性受试者中,口服HER2选择性酪氨酸激酶抑制剂Zongertinib在空腹和进食状态下的相对生物利用度:两项随机、开放标签、交叉研究的结果

Pereira, Hélène; Wölke, Stefan; Sadrolhefazi, Behbood; Esmaeili, Habib; Wind, Sven; Gan, Guanfa; Müller, Fabian; Minich, David; Bader, Kerstin; Grempler, Rolf; Law, Yeuk Ki; Roessner, Philipp M

Pistacia atlantica can improve oxidative status in patients with metabolic dysfunction-associated fatty liver disease

大西洋黄连木可以改善代谢功能障碍相关脂肪肝患者的氧化状态

Mostafaei, Roghayeh; Nachvak, Seyed Mostafa; Saber, Amir; Jalilian, Nazanin; Mahaki, Behzad; Salehi, Mohammad Gharib; Behbood, Leila; Ghorbani, Zahra; Rahimi, Somayeh

The effect of carbamazepine, a strong CYP3A inducer, on the pharmacokinetics of zongertinib in healthy male volunteers

卡马西平(一种强效CYP3A诱导剂)对健康男性志愿者体内宗格替尼药代动力学的影响

Tian, Xiaofan; Esmaeili, Habib; Minich, David; Seitz, Friedeborg; Roessner, Philipp M; Wind, Sven; Grempler, Rolf; Gan, Guanfa; Chan, Tom S; Mahmoudi, Mazyar; Sadrolhefazi, Behbood; Müller, Fabian

Evaluation of heparin gel's effects on stage II pressure ulcers: a randomized controlled trial

评估肝素凝胶对 II 期压疮的疗效:一项随机对照试验

Khani, Raheleh; Behbood, Leila; Fallahi, Masoud; Rezaeian, Shahab; Shahbazi, Foroud

Research into the interplay between EFL teachers' professional identity and EFL students' grit in Libya

利比亚英语教师职业认同与英语学习者毅力之间相互作用的研究

Taha, Ayman Riheel Alnaas; Mohammadzadeh, Behbood; Hamed, Muftah

The Na+/K+-ATPase generically enables deterministic bursting in class I neurons by shearing the spike-onset bifurcation structure

Na+/K+-ATPase 通过剪切尖峰起始分岔结构,通常能够使 I 类神经元产生确定性的爆发式放电。

Behbood, Mahraz; Lemaire, Louisiane; Schleimer, Jan-Hendrik; Schreiber, Susanne