日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Sensitized ENU Mutagenesis Screen for Thrombosis Modifiers Identifies Suppressor Variants in Non-mutagenized Parental Generations Due to Antithrombotic Selective Pressures

针对血栓形成修饰因子的敏感ENU诱变筛选，由于抗血栓选择压力，在未诱变亲代中发现了抑制性变异体。

期刊:
影响因子:
doi:10.64898/2026.01.25.701592
Brake, Marisa A; Cleuren, Audrey C; Torres, Sydney; van der Ent, Martijn A; Zhu, Guojing; Kulchycki, Justin; Parsons, Tyler M; Schneider, Caitlin D; Jurek, Adrianna M; MacFadyen, Kailey; Siebert, Amy E; Siemieniak, David R; Timms, Andrew E; Beier, David R; Westrick, Randal J
心血管
发表日期：2026
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The response to kidney injury is epigenetically regulated through the activation of bivalent genes

肾损伤的反应是通过激活二价基因进行表观遗传调控的。

期刊:
影响因子:
doi:10.1152/ajprenal.00367.2025
Tickman, Benjamin I; McDonald, Jacquelyn R; McCarthy, Ryan; Suh, Kiheon; Okamura, Daryl M; Houghtaling, Scott R; Collins, Sarah J; Bae, Yeji; Beier, David R; Majesky, Mark W; Nguyen, Elizabeth Dong
信号转导
毒理研究
表观遗传
肾损伤
发表日期：2026
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A systems genetics approach identifies roles for proteasome factors in heart development and congenital heart defects.

系统遗传学方法揭示了蛋白酶体因子在心脏发育和先天性心脏缺陷中的作用

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1011579
Farr Gist H III, Reid Whitaker, Hasegawa Eva H, Azzam Azzam, Young Isabelle, Li Mona L, Olson Aaron K, Beier David R, Maves Lisa
发育与干细胞
发表日期：2025
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Inhibition of Hedgehog signaling does not mitigate polycystic kidney disease severity in a Pkd1 mutant mouse model.

在 Pkd1 突变小鼠模型中，抑制 Hedgehog 信号传导并不能减轻多囊肾病的严重程度

期刊:Journal of Cell Science
影响因子:3.6
doi:10.1242/jcs.264133
Gombart Sean K, Houghtaling Scott, Ho Tzu-Hua, Beier David R
信号转导
Hedgehog
Mouse
发表日期：2025
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A conditional smoothened (smo) allele on an inbred C57BL/6J genetic background has a hypomorphic smo mutant phenotype

在近交系 C57BL/6J 遗传背景下，条件性 smoothened (smo) 等位基因表现出 smo 突变体低效表型

期刊:Developmental Biology
影响因子:2.1
doi:10.1016/j.ydbio.2024.11.010
Houghtaling, Scott; Gombart, Sean K; Ho, Tzu-Hua; Huang, Grace; Beier, David R
发表日期：2025
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Mammalian organ regeneration in spiny mice

棘鼠的哺乳动物器官再生

期刊:Journal of Muscle Research and Cell Motility
影响因子:1.7
doi:10.1007/s10974-022-09631-3
Okamura, Daryl M; Nguyen, Elizabeth D; Collins, Sarah J; Yoon, Kevin; Gere, Joshua B; Weiser-Evans, Mary C M; Beier, David R; Majesky, Mark W
发表日期：2023
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Applicability of the Mutation-Selection Balance Model to Population Genetics of Heterozygous Protein-Truncating Variants in Humans

突变-选择平衡模型在人类杂合蛋白截短变异群体遗传学中的适用性

期刊:Molecular Biology and Evolution
影响因子:5.3
doi:10.1093/molbev/msz092
Weghorn, Donate; Balick, Daniel J; Cassa, Christopher; Kosmicki, Jack A; Daly, Mark J; Beier, David R; Sunyaev, Shamil R
Human
发表日期：2019
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Estimating the selective effects of heterozygous protein-truncating variants from human exome data

利用人类外显子组数据估算杂合子蛋白质截短变异的选择性效应

期刊:Nature Genetics
影响因子:29
doi:10.1038/ng.3831
Cassa, Christopher A; Weghorn, Donate; Balick, Daniel J; Jordan, Daniel M; Nusinow, David; Samocha, Kaitlin E; O'Donnell-Luria, Anne; MacArthur, Daniel G; Daly, Mark J; Beier, David R; Sunyaev, Shamil R
发表日期：2017
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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

在肾痨模型中，通过药物或基因手段抑制 CDK5 来缩短纤毛长度可减轻多囊肾病。

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddw093
Husson, Hervé; Moreno, Sarah; Smith, Laurie A; Smith, Mandy M; Russo, Ryan J; Pitstick, Rose; Sergeev, Mikhail; Ledbetter, Steven R; Bukanov, Nikolay O; Lane, Monica; Zhang, Kate; Billot, Katy; Carlson, George; Shah, Jagesh; Meijer, Laurent; Beier, David R; Ibraghimov-Beskrovnaya, Oxana
CDK5
发表日期：2016
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High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease

在多囊肾病幼年囊性肾（jck）小鼠模型中，对影响疾病严重程度的修饰基因位点进行高分辨率基因定位

期刊:Mammalian Genome
影响因子:2.7
doi:10.1007/s00335-016-9633-z
Beier, David R
发表日期：2016
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