日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study

多发性硬化症与肠道菌群：来自多发性硬化症双胞胎回肠的毛螺菌科细菌可诱发无菌转基因小鼠出现类似多发性硬化症的疾病——一项无偏倚的功能研究

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2419689122
Yoon, Hongsup; Gerdes, Lisa Ann; Beigel, Florian; Sun, Yihui; Kövilein, Janine; Wang, Jiancheng; Kuhlmann, Tanja; Flierl-Hecht, Andrea; Haller, Dirk; Hohlfeld, Reinhard; Baranzini, Sergio E; Wekerle, Hartmut; Peters, Anneli
微生物学
肠道菌群
神经科学
多发性硬化症
发表日期：2025
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Autoantibody Profiling in Ulcerative Colitis: Identification of Early Immune Signatures and Disease-Associated Antigens for Improved Diagnosis and Monitoring

溃疡性结肠炎自身抗体谱分析：识别早期免疫特征和疾病相关抗原，以改进诊断和监测

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26094086
Weinhaeusel, Andreas; Huber, Jasmin; Schoenthaler, Silvia; Beigel, Florian; Noehammer, Christa; Vierlinger, Klemens; Siebeck, Matthias; Gropp, Roswitha
结肠炎
肠炎
免疫/内分泌
发表日期：2025
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CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites

CCL20在炎症性肠病中表达升高，而维生素D代谢物可减弱其表达。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-05094-x
Stallhofer, Johannes; Reichl, Felix; Lauseker, Michael; Waldenmaier, Lisa; Török, Helga Paula; Mayerle, Julia; Olszak, Torsten; Schnitzler, Fabian; Frasheri, Iris; Breiteneicher, Simone; Brand, Stephan; Stallmach, Andreas; Diegelmann, Julia; Beigel, Florian
炎症
炎症/感染
CCL2
代谢
CCL20
发表日期：2025
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Humanized NSG Mouse Models as a Preclinical Tool for Translational Research in Inflammatory Bowel Diseases

人源化 NSG 小鼠模型作为炎症性肠病转化研究的临床前工具

期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms241512348
Veronika Weß, Paula Schuster-Winkelmann, Yasemin Hazal Karatekin, Simge Malik, Florian Beigel, Florian Kühn, Roswitha Gropp
免疫
肠炎
HGF
发表日期：2023
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It is not NOD2 - genetic and clinical risk factors for postoperative complications following ileocolic resection in Crohn's disease

并非NOD2基因——克罗恩病回结肠切除术后并发症的遗传和临床风险因素

期刊:International Journal of Colorectal Disease
影响因子:2.3
doi:10.1007/s00384-022-04223-6
Schardey, Josefine; Zehl, Sophie; Kappenberger, Alina S; Zimmermann, Petra; Beigel, Florian; Schiergens, Tobias S; Kasparek, Michael S; Kühn, Florian; Werner, Jens; Wirth, Ulrich
克罗恩病
NOD2
发表日期：2022
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The Combination of Patient Profiling and Preclinical Studies in a Mouse Model Based on NOD/Scid IL2Rγ null Mice Reconstituted With Peripheral Blood Mononuclear Cells From Patients With Ulcerative Colitis May Lead to Stratification of Patients for Treatment With Adalimumab

结合患者特征分析和基于NOD/Scid IL2Rγ基因敲除小鼠（用溃疡性结肠炎患者外周血单核细胞重建）的小鼠模型临床前研究，可能有助于对患者进行分层，以便使用阿达木单抗进行治疗。

期刊:Inflammatory Bowel Diseases
影响因子:4.3
doi:10.1093/ibd/izz284
Jodeleit, Henrika; Caesar, Janina; Villarroel Aguilera, Christina; Sterz, Sebastian; Holdt, Lesca; Beigel, Florian; Stallhofer, Johannes; Breiteneicher, Simone; Bartnik, Eckart; Siebeck, Matthias; Gropp, Roswitha
IL2
肠炎
单核细胞
细胞生物学
Mouse
结肠炎
发表日期：2020
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Autoantibodies as diagnostic markers and potential drivers of inflammation in ulcerative colitis

自身抗体作为溃疡性结肠炎的诊断标志物和潜在炎症驱动因素

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0228615
Jodeleit, Henrika; Milchram, Lisa; Soldo, Regina; Beikircher, Gabriel; Schönthaler, Silvia; Al-Amodi, Omar; Wolf, Eckhard; Beigel, Florian; Weinhäusel, Andreas; Siebeck, Matthias; Gropp, Roswitha
炎症
肠炎
炎症/感染
结肠炎
免疫/内分泌
发表日期：2020
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Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery

所有携带NOD2基因p.Leu1007fsX1008纯合突变且患有克罗恩病并有吸烟史的患者，均表现出一致且极具侵袭性的疾病表型，最终导致回肠狭窄，需要手术治疗。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0236421
Schnitzler, Fabian; Friedrich, Matthias; Angelberger, Marianne; Diegelmann, Julia; Stallhofer, Johannes; Wolf, Christiane; Dütschler, Joel; Truniger, Samuel; Olszak, Torsten; Beigel, Florian; Tillack, Cornelia; Lohse, Peter; Brand, Stephan
克罗恩病
NOD2
发表日期：2020
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CD1a-Expressing Monocytes as Mediators of Inflammation in Ulcerative Colitis

CD1a表达单核细胞在溃疡性结肠炎炎症中发挥介质作用

期刊:Inflammatory Bowel Diseases
影响因子:4.3
doi:10.1093/ibd/izy073
Al-Amodi, Omar; Jodeleit, Henrika; Beigel, Florian; Wolf, Eckhard; Siebeck, Matthias; Gropp, Roswitha
细胞生物学
结肠炎
肠炎
炎症/感染
Immunology/Inflammation
炎症
单核细胞
发表日期：2018
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The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.

骨桥蛋白（OPN/SPP1）单倍型在克罗恩病易感性中的作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0029309
Glas Jürgen, Seiderer Julia, Bayrle Corinna, Wetzke Martin, Fries Christoph, Tillack Cornelia, Olszak Torsten, Beigel Florian, Steib Christian, Friedrich Matthias, Diegelmann Julia, Czamara Darina, Brand Stephan
骨科研究
发表日期：2011
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