日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions

尿石素A可改善阿尔茨海默病患者的认知功能,并恢复线粒体自噬和溶酶体功能。

Yujun Hou,Xixia Chu,Jae-Hyeon Park,Qing Zhu,Mansoor Hussain,Zhiquan Li,Helena Borland Madsen,Beimeng Yang,Yong Wei,Yue Wang,Evandro F Fang,Deborah L Croteau,Vilhelm A Bohr

RecQ dysfunction contributes to social and depressive-like behavior and affects aldolase activity in mice

RecQ 功能障碍会导致小鼠的社交和抑郁样行为并影响醛缩酶活性

Yujun Hou, Jae-Hyeon Park, Xiuli Dan, Xixia Chu, Beimeng Yang, Mansoor Hussain, Deborah L Croteau, Vilhelm A Bohr

Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction

重新平衡不平衡的 NAD 代谢可改善端粒功能障碍的影响

Chongkui Sun #, Kun Wang #, Amanda J Stock, Yi Gong, Tyler G Demarest, Beimeng Yang, Neelam Giri, Lea Harrington, Blanche P Alter, Sharon A Savage, Vilhelm A Bohr, Yie Liu

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease

线粒体自噬抑制β-淀粉样蛋白和tau蛋白病理,并逆转阿尔茨海默病模型中的认知缺陷

Evandro F Fang # ,Yujun Hou # ,Konstantinos Palikaras # ,Bryan A Adriaanse ,Jesse S Kerr ,Beimeng Yang ,Sofie Lautrup ,Md Mahdi Hasan-Olive ,Domenica Caponio ,Xiuli Dan ,Paula Rocktäschel ,Deborah L Croteau ,Mansour Akbari ,Nigel H Greig ,Tormod Fladby ,Hilde Nilsen ,M Zameel Cader ,Mark P Mattson ,Nektarios Tavernarakis ,Vilhelm A Bohr

NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome

NAD+ 增强疗法可恢复线粒体自噬并限制沃纳综合征患者的加速衰老

Evandro F Fang, Yujun Hou, Sofie Lautrup, Martin Borch Jensen, Beimeng Yang, Tanima SenGupta, Domenica Caponio, Rojyar Khezri, Tyler G Demarest, Yahyah Aman, David Figueroa, Marya Morevati, Ho-Joon Lee, Hisaya Kato, Henok Kassahun, Jong-Hyuk Lee, Deborah Filippelli, Mustafa Nazir Okur, Aswin Mangeri

NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress

NEIL1 刺激神经发生并抑制应激后的神经炎症

Beimeng Yang, David M Figueroa, Yujun Hou, Mansi Babbar, Stephanie L Baringer, Deborah L Croteau, Vilhelm A Bohr

Nicotinamide adenine dinucleotide suppresses epileptogenesis at an early stage

烟酰胺腺嘌呤二核苷酸抑制早期癫痫发生

Juan Liu, Beimeng Yang, Pei Zhou, Yingying Kong, Weiwei Hu, Geng Zhu, Weihai Ying, Weidong Li, Yun Wang, Shengtian Li

24-hour-restraint stress induces long-term depressive-like phenotypes in mice

24小时束缚应激可诱导小鼠出现长期抑郁样表型。

Xixia Chu ,Ying Zhou ,Zhiqiang Hu ,Jingyu Lou ,Wei Song ,Jing Li ,Xiao Liang ,Chen Chen ,Shuai Wang ,Beimeng Yang ,Lei Chen ,Xu Zhang ,Jinjing Song ,Yujie Dong ,Shiqing Chen ,Lin He ,Qingguo Xie ,Xiaoping Chen ,Weidong Li