日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Gut microbiota modulation via repeated donor fecal transplantation improves motor and gastrointestinal symptoms in drug-naïve Parkinson's disease: a randomized phase 2 trial

通过重复供体粪便移植调节肠道菌群可改善未经药物治疗的帕金森病患者的运动和胃肠道症状：一项随机 II 期试验

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02604-9
Zhang, Rui; Feng, Renyi; Wang, Jiuqi; Chen, Yongkang; Liu, Han; Zhu, Qingyong; Tian, Haiyan; Qin, Chi; Teng, Junfang; Tang, Beisha; Wu, Min; Zeng, Jinsheng; Wu, Erxi; Ding, Xuebing; Wang, Xuejing
微生物学
肠道菌群
帕金森
神经科学
发表日期：2026
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Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.

利用 CRISPR/Cas9 技术精确切除 NOTCH2NLC 中扩增的 GGC 重复序列，用于治疗神经元核内包涵体病。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68385-5
Xie Nina, Pan Yongcheng, Tong Huichun, Lin Yingqi, Jiang Ying, Wang Zhiqin, Wan Juan, Zhang Wendiao, Wang Xinhui, Sun Xiaobo, Yan Sen, Yin Peng, Sun Qiying, Qi Chengzhi, Tian Yun, Shen Lu, Jiang Hong, Liang Desheng, Tang Beisha, Li Shihua, Li Xiao-Jiang, Liu Qiong
神经科学
OTC
CAS9
NOTCH
Notch
发表日期：2026
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Gene4Denovo2: an updated platform for human de novo mutations discovery and interpretation

Gene4Denovo2：一个用于发现和解读人类新生突变的更新平台

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf980
Zhu, Zhaopo; Yu, Pei; Mao, Xinxin; Liu, Chenbin; Li, Kuokuo; Zhou, Qiao; Wang, Yijing; Luo, Tengfei; Xiang, Xudong; Zhu, Yixiao; Wu, Dai; Jian, Xingxing; Li, Bin; Tang, Beisha; Xia, Kun; Zhao, Guihu; Li, Jinchen
发表日期：2026
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Shared genetic architecture between sleep traits and cardiometabolic diseases

睡眠特征与心血管代谢疾病之间存在共同的遗传结构

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106220
Zhang, Yuan; Jian, Shijie; Ouyang, Haiyan; Purushotham, Yogesh; Yu, Qiao; Tang, Beisha; Gottlieb, Daniel J; Sofer, Tamar; Yi, Minhan
代谢
发表日期：2026
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Short tandem repeat expansions in patients with neurodegenerative dementia

神经退行性痴呆患者的短串联重复序列扩增

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106190
Zhu, Yuan; Xiao, Xuewen; Liu, Yiliang; Wang, Zheng; Luo, Tengfei; Xu, Tianyan; Yang, Qijie; Hao, Xiaoli; Zhang, Cong; Zhang, Sizhe; Luo, Shilin; Zhou, Yafang; Liao, Xinxin; Tian, Yun; Weng, Ling; Fang, Liangjuan; Tang, Beisha; Jiao, Bin; Li, Jinchen; Shen, Lu
神经科学
发表日期：2026
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Plasma p-tau species are elevated in presymptomatic and symptomatic neuronal intranuclear inclusion disease

血浆磷酸化tau蛋白在无症状和有症状的神经元核内包涵体病中均升高。

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106127
Zhang, Sizhe; Jiao, Bin; Zeng, Yan; Sun, Qiying; Chen, Xiaoyu; Zhang, Weiwei; Ouyang, Ziyu; Xiao, Qiao; Zhou, Lu; Li, Yunni; Weng, Ling; Du, Juan; Xu, Qian; Yang, Yang; Zhang, Mengqi; Zeng, Qiuming; Fang, Liangjuan; Long, Hongyu; Xie, Yuanyuan; Chen, Si; Feng, Li; Huang, Qing; Long, Lili; Zhou, Yafang; Yi, Fang; Hu, Yacen; Liu, Qiong; Pan, Yongcheng; Zhou, Lin; Li, Yulai; Hu, Shuo; Guo, Jifeng; Wang, Junling; Jiang, Hong; Xu, Hongwei; Duan, Ranhui; Tang, Beisha; Tian, Yun; Shen, Lu
信号转导
磷酸化
神经科学
发表日期：2026
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Large-scale profiling of blood microbial signatures in patients with Parkinson's disease and its association with disease progression: a cross-sectional study

帕金森病患者血液微生物特征的大规模分析及其与疾病进展的关系：一项横断面研究

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106224
Jian, Xingxing; Yu, Pei; Zhang, Yi; Pan, Hongxu; Wu, Keman; Zhang, Hongxi; Zhang, Hao; Huang, Yuanfeng; Zhao, Yuwen; Wang, Yige; Wang, Yijing; Zhou, Qiao; Zhang, Xiaotuan; Zhao, Guihu; Li, Bin; Guo, Jifeng; Xia, Kun; Tang, Beisha; Li, Jinchen
微生物学
帕金森
神经科学
发表日期：2026
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Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer's disease.

血浆中的神经元 PPP2R5C 是一种潜在的阿尔茨海默病早期诊断生物标志物。

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2026.102631
Luo Shilin, Liu Hui, Xiao Tingting, Li Yunni, Liu Xixi, Xiao Xuewen, Liao Xinxin, Liu Yingzi, Zhou Yafang, Wang Jun-Ling, Guo Jifeng, Tu Tian, Yan Xiaoxin, Tang Beisha, Zhang Zhentao, Jiao Bin, Shen Lu
神经科学
发表日期：2026
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The anti-NMDAR1 antibodies and IL-17 signaling pathway shape NMDAR encephalitis

抗NMDAR1抗体和IL-17信号通路在NMDAR脑炎中发挥作用

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03434-x
Xu, Zhenhong; Yan, Hongye; Wang, Bo; Wan, Juan; Wang, Huimin; Xia, Ye; Liu, Yong U; Wang, Xuejing; Wu, Heng; Jiang, Jiamei; Zeng, Lin; Tang, Beisha; Meng, Qingtuan
信号转导
脑炎
神经科学
IL-17
发表日期：2026
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Multidimensional modeling of biological aging: integrating gait, eye movement, rest-state functional connectivity, and plasma biomarkers in non-dementia older adults

生物衰老的多维建模：整合非痴呆老年人的步态、眼动、静息态功能连接和血浆生物标志物

期刊:Jpad-Journal of Prevention of Alzheimers Disease
影响因子:7.8
doi:10.1016/j.tjpad.2026.100566
Lin, Jingyi; Liu, Yiliang; Ouyang, Ziyu; Yang, Xuan; Zhang, Sizhe; Xu, Tianyan; Yang, Qijie; Zhu, Yuan; Wan, Meidan; Xiao, Xuewen; Fan, Xiangmin; Tang, Beisha; Shen, Lu; Jiao, Bin; Luo, Shilin
衰老
发表日期：2026
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