日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.

抑制肌醇激酶Itpkb可增强淋巴细胞中的钙信号传导,并揭示治疗自身免疫性疾病的新策略

Miller Andrew T, Dahlberg Carol, Sandberg Mark L, Wen Ben G, Beisner Daniel R, Hoerter John A H, Parker Albert, Schmedt Christian, Stinson Monique, Avis Jacqueline, Cienfuegos Cynthia, McPate Mark, Tranter Pamela, Gosling Martin, Groot-Kormelink Paul J, Dawson Janet, Pan Shifeng, Tian Shin-Shay, Seidel H Martin, Cooke Michael P

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

膜内蛋白酶Sppl2a通过切割不变链,对B细胞和树突状细胞的发育和存活至关重要。

Beisner, Daniel R; Langerak, Petra; Parker, Albert E; Dahlberg, Carol; Otero, Francella J; Sutton, Sue E; Poirot, Laurent; Barnes, Whitney; Young, Michael A; Niessen, Sherry; Wiltshire, Tim; Bodendorf, Ursula; Martoglio, Bruno; Cravatt, Benjamin; Cooke, Michael P

Foxo transcription factors control regulatory T cell development and function

Foxo转录因子调控调节性T细胞的发育和功能

Kerdiles, Yann M; Stone, Erica L; Beisner, Daniel R; McGargill, Maureen A; Ch'en, Irene L; Stockmann, Christian; Katayama, Carol D; Hedrick, Stephen M

Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells.

转录因子 Foxo3 通过调节树突状细胞的功能来控制 T 细胞免疫反应的强度

Dejean Anne S, Beisner Daniel R, Ch'en Irene L, Kerdiles Yann M, Babour Anna, Arden Karen C, Castrillon Diego H, DePinho Ronald A, Hedrick Stephen M