TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms
TDP43 的自身调控产生显性负性异构体,这些异构体受到转录和翻译后机制的严格控制。
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2024.115113
Megan M Dykstra,Kaitlin Weskamp,Nicolás B Gómez,Jacob Waksmacki,Elizabeth Tank,M Rebecca Glineburg,Allison Snyder,Emile Pinarbasi,Michael Bekier,Xingli Li,Morgan R Miller,Jen Bai,Shameena Shahzad,Neha Nedumaran,Clare Wieland,Corey Stewart,Sydney Willey,Nikolas Grotewold,Jonathon McBride,John J Moran,Aditya V Suryakumar,Michael Lucas,Peter M Tessier,Michael Ward,Peter K Todd,Sami J Barmada