日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia

对人脑外显子包含机制的解码揭示了神经元中比胶质细胞中更为多样化的剪接机制。

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-026-04015-z
Michielsen, Lieke; Hsu, Justine; Joglekar, Anoushka; Belchikov, Natan; Reinders, Marcel J T; Tilgner, Hagen U; Mahfouz, Ahmed
胶质细胞
细胞生物学
神经科学
发表日期：2026
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A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.

接近单细胞分辨率的空间长读长方法揭示了不同皮层层和细胞类型中剪接和多聚腺苷酸化位点的发育调控

期刊:
影响因子:
doi:10.1101/2025.06.10.658877
Foord Careen, Prjibelski Andrey D, Hu Wen, Michielsen Lieke, Vandelli Andrea, Narykov Oleksandr, Evans Brian, Hsu Justine, Belchikov Natan, Jarroux Julien, He Yi, Ross M Elizabeth, Hajirasouliha Iman, Tartaglia Gian Gaetano, Korkin Dmitry, Tomescu Alexandru I, Tilgner Hagen U
细胞生物学
发表日期：2025
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Understanding isoform expression by pairing long-read sequencing with single-cell and spatial transcriptomics

通过将长读长测序与单细胞和空间转录组学相结合来了解异构体表达

期刊:Genome Research
影响因子:5.5
doi:10.1101/gr.279640.124
Belchikov, Natan; Hsu, Justine; Li, Xiang Jennie; Jarroux, Julien; Hu, Wen; Joglekar, Anoushka; Tilgner, Hagen U
细胞生物学
单细胞
发表日期：2024
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ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's Disease

ScISOr-ATAC揭示了皮层区域、进化过程中以及阿尔茨海默病中匹配细胞类型之间趋同和趋异的剪接和染色质特异性。

期刊:
影响因子:
doi:10.1101/2024.02.24.581897
Hu, Wen; Foord, Careen; Hsu, Justine; Fan, Li; Corley, Michael J; Bhatia, Tarun N; Xu, Siwei; Belchikov, Natan; He, Yi; Pang, Alina Ps; Lanjewar, Samantha N; Jarroux, Julien; Joglekar, Anoushka; Milner, Teresa A; Ndhlovu, Lishomwa C; Zhang, Jing; Butelman, Eduardo; Sloan, Steven A; Lee, Virginia My; Gan, Li; Tilgner, Hagen U
阿尔茨海默症
细胞生物学
发表日期：2024
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Ariadne: synthetic long read deconvolution using assembly graphs

Ariadne：利用组装图进行合成长读反卷积

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-023-03033-5
Mak, Lauren; Meleshko, Dmitry; Danko, David C; Barakzai, Waris N; Maharjan, Salil; Belchikov, Natan; Hajirasouliha, Iman
发表日期：2023
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