The D75N and P161S Mutations in the C0-C2 Fragment of cMyBP-C Associated with Hypertrophic Cardiomyopathy Disturb the Thin Filament Activation, Nucleotide Exchange in Myosin, and Actin-Myosin Interaction
cMyBP-C C0-C2片段中的D75N和P161S突变与肥厚型心肌病相关,这些突变会扰乱细丝激活、肌球蛋白核苷酸交换以及肌动蛋白-肌球蛋白相互作用。
期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms252011195
Kochurova, Anastasia M; Beldiia, Evgenia A; Nefedova, Victoria V; Yampolskaya, Daria S; Koubassova, Natalia A; Kleymenov, Sergey Y; Antonets, Julia Y; Ryabkova, Natalia S; Katrukha, Ivan A; Bershitsky, Sergey Y; Matyushenko, Alexander M; Kopylova, Galina V; Shchepkin, Daniil V