日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)

选择性PPARδ调节剂改善线粒体功能:杜氏肌营养不良症(DMD)的潜在治疗方法

Lagu, Bharat; Kluge, Arthur F; Tozzo, Effie; Fredenburg, Ross; Bell, Eric L; Goddeeris, Matthew M; Dwyer, Peter; Basinski, Andrew; Senaiar, Ramesh S; Jaleel, Mahaboobi; Tiwari, Nirbhay Kumar; Panigrahi, Sunil K; Krishnamurthy, Narasimha Rao; Takahashi, Taisuke; Patane, Michael A

Global microRNA depletion suppresses tumor angiogenesis.

全球microRNA耗竭抑制肿瘤血管生成

Chen Sidi, Xue Yuan, Wu Xuebing, Le Cong, Bhutkar Arjun, Bell Eric L, Zhang Feng, Langer Robert, Sharp Phillip A

Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.

二甲双胍会降低葡萄糖氧化,并增加前列腺癌细胞对还原性谷氨酰胺代谢的依赖性

Fendt Sarah-Maria, Bell Eric L, Keibler Mark A, Davidson Shawn M, Wirth Gregory J, Fiske Brian, Mayers Jared R, Schwab Matthias, Bellinger Gary, Csibi Alfredo, Patnaik Akash, Blouin Marie Jose, Cantley Lewis C, Guarente Leonard, Blenis John, Pollak Michael N, Olumi Aria F, Vander Heiden Matthew G, Stephanopoulos Gregory

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS

高氧诱导的过早衰老需要p53和pRb,但不需要线粒体基质活性氧(ROS)。

Klimova, Tatyana A; Bell, Eric L; Shroff, Emelyn H; Weinberg, Frank D; Snyder, Colleen M; Dimri, Goberdan P; Schumacker, Paul T; Budinger, G R Scott; Chandel, Navdeep S

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

线粒体复合物III的Qo位点对于通过活性氧的产生来传递缺氧信号是必需的。

Bell, Eric L; Klimova, Tatyana A; Eisenbart, James; Moraes, Carlos T; Murphy, Michael P; Budinger, G R Scott; Chandel, Navdeep S