The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons to amyloid beta and phosphorylated tau-induced neuronal dysfunction
tau 亚型 1N4R 使 MAPT 敲除的人类 iPSC 衍生神经元更容易受到淀粉样蛋白 β 和磷酸化 tau 诱导的神经元功能障碍的影响。
期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.14403
Buchholz, Sarah; Kabbani, Mohamed Aghyad Al; Bell-Simons, Michael; Kluge, Lena; Cagmak, Cagla; Klimek, Jennifer; Haag, Natja; Iohan, Lukas C; Coulon, Audrey; Costa, Marcos R; Kilinc, Devrim; Zempel, Hans
