日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SUMO1 degrader induces ER stress and ROS accumulation through deSUMOylation of TCF4 and inhibition of its transcription of StarD7 in colon cancer

SUMO1降解剂通过TCF4的去SUMO化及其对StarD7转录的抑制,诱导结肠癌中的内质网应激和活性氧积累。

Yin Quan Zhao ,Hong Ri Jin ,Daeho Kim ,Sung Han Jung ,Sheng Liu ,Jun Wan ,Ho-Yin Lo ,Xue Qi Fu ,Quan Wang ,Chunhai Hao ,Anita C Bellail

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors

小分子降解剂对 SUMO1 进行泛素化和降解可延长患有患者源性肿瘤的小鼠的生存期

Anita C Bellail, Hong Ri Jin, Ho-Yin Lo, Sung Han Jung, Chafiq Hamdouchi, Daeho Kim, Ryan K Higgins, Maximilian Blanck, Carlos le Sage, Benedict C S Cross, Jing Li, Amber L Mosley, Aruna B Wijeratne, Wen Jiang, Manali Ghosh, Yin Quan Zhao, Paula M Hauck, Anantha Shekhar, Chunhai Hao0

PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFκB pathway

PD-1 不依赖于 PD-L1 配体结合,通过 NFκB 通路促进胶质母细胞瘤生长。

Reza Mirzaei ,Ashley Gordon ,Franz J Zemp ,Mehul Kumar ,Susobhan Sarkar ,H Artee Luchman ,Anita C Bellail ,Chunhai Hao ,Douglas J Mahoney ,Jeff F Dunn ,Pinaki Bose ,V Wee Yong

Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor-initiating cells

胶质母细胞瘤微环境中的纤维蛋白原促进脑肿瘤起始细胞的侵袭性。

Lauren Dzikowski ,Reza Mirzaei ,Susobhan Sarkar ,Mehul Kumar ,Pinaki Bose ,Anita Bellail ,Chunhai Hao ,V Wee Yong

SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression

SUMO1 修饰可稳定 CDK6 蛋白并驱动细胞周期和胶质母细胞瘤进展

Anita C Bellail, Jeffrey J Olson, Chunhai Hao

PD-0332991 induces G1 arrest of colorectal carcinoma cells through inhibition of the cyclin-dependent kinase-6 and retinoblastoma protein axis

PD-0332991 通过抑制细胞周期蛋白依赖性激酶 6 和视网膜母细胞瘤蛋白轴诱导结直肠癌细胞 G1 停滞

Chunsheng Li, Ling Qi, Anita C Bellail, Chunhai Hao, Tongjun Liu

Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma

mTOR 和 EGFR 激酶抑制剂联合使用可阻断 mTORC1 和 mTORC2 激酶活性并抑制结直肠癌的进展

Quan Wang, Feng Wei, Chunsheng Li, Guoyue Lv, Guangyi Wang, Tongjun Liu, Anita C Bellail, Chunhai Hao

A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma

A20 泛素连接酶介导的 RIP1 多泛素化抑制 caspase-8 裂解和 TRAIL 诱导的胶质母细胞瘤细胞凋亡

Anita C Bellail, Jeffrey J Olson, Xiaolu Yang, Zhijian J Chen, Chunhai Hao

TRAIL apoptotic pathway-targeted therapies for NSCLC

TRAIL凋亡通路靶向疗法治疗非小细胞肺癌

Bellail, Anita C; Hao, Chunhai

Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis

原发性胶质母细胞瘤细胞caspase-8表达的异质性及对TRAIL诱导的凋亡的反应

Ling Qi, Anita C Bellail, Michael R Rossi, Zhaobin Zhang, Hui Pang, Stephen Hunter, Cynthia Cohen, Carlos S Moreno, Jeffrey J Olson, Shibo Li, Chunhai Hao