Belt Brian A相关文献与解析，生知库 | 链接生命科学的每一步

Ye Jian, Qin Shuyang S, Hughson Angela L, Hannon Gary, Salama Noah A, Vrooman Tara G, Lesch Maggie L, Lesser Sidney, Eckl Sarah L, Jewell Rachel, Benoodt Lauren, Mills Bradley N, Johnston Carl J, Lord Edith, Belt Brian A, Calvi Laura M, Linehan David, Luheshi Nadia, Eyles Jim, Gerber Scott A

肿瘤

发表日期：2025

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Blockade of LIF and PD-L1 Enhances Chemotherapy in Preclinical PDAC Models

阻断 LIF 和 PD-L1 可增强临床前 PDAC 模型中的化疗效果

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers17020204

Ye, Jian; Qin, Shuyang S; Hughson, Angela L; Hannon, Gary; Vrooman, Tara G; Lesch, Maggie L; Eckl, Sarah L; Benoodt, Lauren; Mills, Bradley N; Lord, Edith M; Belt, Brian A; Linehan, David C; Luheshi, Nadia; Eyles, Jim; Gerber, Scott A

Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy

泛赖氨酰氧化酶抑制剂可破坏纤维炎症性肿瘤基质，使胆管癌对化疗更敏感。

期刊:Hepatology Communications

影响因子:4.6

doi:10.1097/HC9.0000000000000502

Burchard, Paul R; Ruffolo, Luis I; Ullman, Nicholas A; Dale, Benjamin S; Dave, Yatee A; Hilty, Bailey K; Ye, Jian; Georger, Mary; Jewell, Rachel; Miller, Christine; De Las Casas, Luis; Jarolimek, Wolfgang; Perryman, Lara; Byrne, Matthew M; Loria, Anthony; Marin, Chelsea; Chávez Villa, Mariana; Yeh, Jen Jen; Belt, Brian A; Linehan, David C; Hernandez-Alejandro, Roberto

Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer

PurIST（一种临床上稳健的单样本肿瘤亚型分类器），用于胰腺癌的肿瘤亚型分类，是一种与肿瘤纯度无关的肿瘤亚型分类器。

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-19-1467

Rashid, Naim U; Peng, Xianlu L; Jin, Chong; Moffitt, Richard A; Volmar, Keith E; Belt, Brian A; Panni, Roheena Z; Nywening, Timothy M; Herrera, Silvia G; Moore, Kristin J; Hennessey, Sarah G; Morrison, Ashley B; Kawalerski, Ryan; Nayyar, Apoorve; Chang, Audrey E; Schmidt, Benjamin; Kim, Hong Jin; Linehan, David C; Yeh, Jen Jen

Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma

一项针对人趋化因子（CC基序）受体2的小分子拮抗剂（PF-04136309）联合白蛋白结合型紫杉醇/吉西他滨一线治疗转移性胰腺导管腺癌的1b期研究

期刊:Investigational New Drugs

影响因子:2.7

doi:10.1007/s10637-019-00830-3

Noel, Marcus; O'Reilly, Eileen M; Wolpin, Brian M; Ryan, David P; Bullock, Andrea J; Britten, Carolyn D; Linehan, David C; Belt, Brian A; Gamelin, Eric C; Ganguly, Bishu; Yin, Donghua; Joh, Tenshang; Jacobs, Ira A; Taylor, Carrie T; Lowery, Maeve A

Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.

包裹免疫治疗药物的微球靶向胰腺导管腺癌的肿瘤引流淋巴结

期刊:Immunological Investigations

影响因子:2.4

doi:10.1080/08820139.2020.1765795

Han Booyeon J, Murphy Joseph D, Qin Shuyang, Ye Jian, Uccello Taylor P, Garrett-Larsen Jesse, Belt Brian A, Prieto Peter A, Egilmez Nejat K, Lord Edith M, Linehan David C, Mills Bradley N, Gerber Scott A

Targeting both tumour-associated CXCR2(+) neutrophils and CCR2(+) macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

靶向肿瘤相关CXCR2(+)中性粒细胞和CCR2(+)巨噬细胞可破坏髓系细胞募集，并改善胰腺导管腺癌的化疗反应。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2017-313738

Nywening, Timothy M; Belt, Brian A; Cullinan, Darren R; Panni, Roheena Z; Han, Booyeon J; Sanford, Dominic E; Jacobs, Ryan C; Ye, Jian; Patel, Ankit A; Gillanders, William E; Fields, Ryan C; DeNardo, David G; Hawkins, William G; Goedegebuure, Peter; Linehan, David C

Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes.

通过调节 CCR2/CCR5 趋化因子轴来提高放射疗法的疗效

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.13287

Connolly Kelli A, Belt Brian A, Figueroa Nathania M, Murthy Aditi, Patel Ankit, Kim Minsoo, Lord Edith M, Linehan David C, Gerber Scott A

A Study of Zoledronic Acid as Neo-Adjuvant, Perioperative Therapy in Patients with Resectable Pancreatic Ductal Adenocarcinoma

唑来膦酸作为可切除胰腺导管腺癌患者新辅助围手术期治疗的研究

期刊:

影响因子:

doi:10.4236/jct.2013.43096

Sanford, Dominic E; Porembka, Matthew R; Panni, Roheena Z; Mitchem, Jonathan B; Belt, Brian A; Plambeck-Suess, Stacey M; Lin, Goldie; Denardo, David G; Fields, Ryan C; Hawkins, William G; Strasberg, Steven M; Lockhart, A Craig; Wang-Gillam, Andrea; Goedegebuure, Simon Peter; Linehan, David C

Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination

疫苗接种后，交叉着装的CD8α+/CD103+树突状细胞可启动CD8+ T细胞。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1203468109

Li, Lijin; Kim, Sojung; Herndon, John M; Goedegebuure, Peter; Belt, Brian A; Satpathy, Ansuman T; Fleming, Timothy P; Hansen, Ted H; Murphy, Kenneth M; Gillanders, William E

Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models.

阻断 LIF 和 PD-L1 可增强 SBRT 在小鼠 PDAC 模型中的抗肿瘤疗效

Blockade of LIF and PD-L1 Enhances Chemotherapy in Preclinical PDAC Models

阻断 LIF 和 PD-L1 可增强临床前 PDAC 模型中的化疗效果

Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy

泛赖氨酰氧化酶抑制剂可破坏纤维炎症性肿瘤基质，使胆管癌对化疗更敏感。

Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer

PurIST（一种临床上稳健的单样本肿瘤亚型分类器），用于胰腺癌的肿瘤亚型分类，是一种与肿瘤纯度无关的肿瘤亚型分类器。

Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma

一项针对人趋化因子（CC基序）受体2的小分子拮抗剂（PF-04136309）联合白蛋白结合型紫杉醇/吉西他滨一线治疗转移性胰腺导管腺癌的1b期研究

Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.

包裹免疫治疗药物的微球靶向胰腺导管腺癌的肿瘤引流淋巴结

Targeting both tumour-associated CXCR2(+) neutrophils and CCR2(+) macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

靶向肿瘤相关CXCR2(+)中性粒细胞和CCR2(+)巨噬细胞可破坏髓系细胞募集，并改善胰腺导管腺癌的化疗反应。

Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes.

通过调节 CCR2/CCR5 趋化因子轴来提高放射疗法的疗效

A Study of Zoledronic Acid as Neo-Adjuvant, Perioperative Therapy in Patients with Resectable Pancreatic Ductal Adenocarcinoma

唑来膦酸作为可切除胰腺导管腺癌患者新辅助围手术期治疗的研究

Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination

疫苗接种后，交叉着装的CD8α+/CD103+树突状细胞可启动CD8+ T细胞。