日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intrathecal or intravenous AAV9-IDUA/RGX-111 at minimal effective dose prevents cardiac, skeletal and neurologic manifestations of murine MPS I.

鞘内或静脉注射最小有效剂量的 AAV9-IDUA/RGX-111 可预防小鼠 MPS I 的心脏、骨骼和神经系统症状

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2024.101369
Belur Lalitha R, Huber Avery K, Mantone Hillary, Robertson Mason, Smith Miles C, Karlen Andrea D, Kitto Kelley F, Ou Li, Whitley Chester B, Braunlin Elizabeth, Furcich Justin, Lund Troy C, Seelig Davis, Fairbanks Carolyn A, Buss Nicholas, Kim Kwi Hye, McIvor R Scott
神经科学
发表日期：2024
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Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine

通过提高脊髓精氨酸水平，可长期逆转啮齿动物的慢性疼痛行为。

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2023.01.022
Peterson, Cristina D; Waataja, Jonathan J; Kitto, Kelley F; Erb, Samuel J; Verma, Harsha; Schuster, Daniel J; Churchill, Caroline C; Riedl, Maureen S; Belur, Lalitha R; Wolf, Daniel A; McIvor, R Scott; Vulchanova, Lucy; Wilcox, George L; Fairbanks, Carolyn A
神经科学
发表日期：2023
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Adeno-associated virus-mediated gene transfer of arginine decarboxylase to the central nervous system prevents opioid analgesic tolerance

腺相关病毒介导的精氨酸脱羧酶基因转移至中枢神经系统可预防阿片类镇痛药耐受性

期刊:Frontiers in Pain Research
影响因子:2.7
doi:10.3389/fpain.2023.1269017
Churchill, Caroline C; Peterson, Cristina D; Kitto, Kelley F; Pflepsen, Kelsey R; Belur, Lalitha R; McIvor, R Scott; Vulchanova, Lucy; Wilcox, George L; Fairbanks, Carolyn A
微生物学
神经科学
发表日期：2023
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Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I

比较脑室内、鞘内和鼻内三种途径给予AAV9载体治疗小鼠I型粘多糖贮积症神经系统疾病的基因治疗效果

期刊:Frontiers in Molecular Neuroscience
影响因子:3.8
doi:10.3389/fnmol.2021.618360
Belur, Lalitha R; Romero, Megan; Lee, Junggu; Podetz-Pedersen, Kelly M; Nan, Zhenhong; Riedl, Maureen S; Vulchanova, Lucy; Kitto, Kelley F; Fairbanks, Carolyn A; Kozarsky, Karen F; Orchard, Paul J; Frey, William H 2nd; Low, Walter C; McIvor, R Scott
基因治疗
神经科学
发表日期：2021
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Intravenous delivery for treatment of mucopolysaccharidosis type I: A comparison of AAV serotypes 9 and rh10

静脉注射治疗I型粘多糖贮积症：AAV血清型9和rh10的比较

期刊:Molecular Genetics and Metabolism Reports
影响因子:1.9
doi:10.1016/j.ymgmr.2020.100604
Belur, Lalitha R; Podetz-Pedersen, Kelly M; Tran, Thuy An; Mesick, Joshua A; Singh, Nathaniel M; Riedl, Maureen; Vulchanova, Lucy; Kozarsky, Karen F; McIvor, R Scott
发表日期：2020
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Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I

鼻内腺相关病毒介导的人艾杜糖醛酸酶基因递送及在中枢神经系统中的表达：一种预防I型粘多糖贮积症神经系统疾病的非侵入性有效方法

期刊:Human Gene Therapy
影响因子:4
doi:10.1089/hum.2017.187
Belur, Lalitha R; Temme, Alexa; Podetz-Pedersen, Kelly M; Riedl, Maureen; Vulchanova, Lucy; Robinson, Nicholas; Hanson, Leah R; Kozarsky, Karen F; Orchard, Paul J; Frey, William H 2nd; Low, Walter C; McIvor, R Scott
Human
发表日期：2017
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Direct gene transfer to the CNS prevents emergence of neurologic disease in a murine model of mucopolysaccharidosis type I

在I型粘多糖贮积症小鼠模型中，直接向中枢神经系统进行基因转移可预防神经系统疾病的发生。

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2011.02.015
Wolf, Daniel A; Lenander, Andrew W; Nan, Zhenhong; Belur, Lalitha R; Whitley, Chester B; Gupta, Pankaj; Low, Walter C; McIvor, R Scott
神经科学
发表日期：2011
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Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons

静脉输注睡美人转座子的聚乙烯亚胺复合物后肺和肝脏中的基因表达

期刊:Human Gene Therapy
影响因子:4
doi:10.1089/hum.2009.128
Podetz-Pedersen, Kelly M; Bell, Jason B; Steele, Terry W J; Wilber, Andrew; Shier, W Thomas; Belur, Lalitha R; McIvor, R Scott; Hackett, Perry B
发表日期：2010
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Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture

通过腰椎穿刺直接鞘内注射腺相关病毒介导的基因转移至感觉神经元的差异

期刊:Molecular Pain
影响因子:2.8
doi:10.1186/1744-8069-6-31
Vulchanova, Lucy; Schuster, Daniel J; Belur, Lalitha R; Riedl, Maureen S; Podetz-Pedersen, Kelly M; Kitto, Kelley F; Wilcox, George L; McIvor, R Scott; Fairbanks, Carolyn A
微生物学
神经科学
发表日期：2010
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Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1 : bFGFR-1 mediates AAV2 transduction of Purkinje cells

腺相关病毒2型载体：成纤维细胞生长因子受体1介导小脑浦肯野细胞的体内转导和长期表达：bFGFR-1介导AAV2对浦肯野细胞的转导

期刊:Archives of Virology
影响因子:2.5
doi:10.1007/s00705-008-0222-7
Belur, Lalitha R; Kaemmerer, William F; McIvor, R Scott; Low, Walter C
信号转导
微生物学
神经科学
成纤维细胞
细胞生物学
发表日期：2008
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