日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Application of Biological Modifiers to a Multiplexed, Human Cell-Based DNA Damage Assay Provides Mechanistic Information on Genotoxicity and Molecular Targets

将生物修饰剂应用于多重人细胞DNA损伤检测,可提供基因毒性和分子靶点的机制信息

Bryce, Steven M; Avlasevich, Svetlana L; Conrad, Adam; Hall, Nikki E; Tichenor, Kyle; Briggs, Erica; Dertinger, Stephen D; Bemis, Jeffrey C

Mitigation of Volatile Chemicals' Effect on Adjacent Microtiter Plate Wells

减轻挥发性化学物质对相邻微孔板孔的影响

Avlasevich, Svetlana L; Briggs, Erica; Tichenor, Kyle; Conrad, Adam; Hall, Nikki; Bryce, Steven M; Bemis, Jeffrey C; Dertinger, Stephen D

In vitro human cell-based aneugen molecular mechanism assay

体外人细胞非整倍体生成素分子机制检测

Hall, Nikki E; Tichenor, Kyle; Bryce, Steven M; Bemis, Jeffrey C; Dertinger, Stephen D

Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays

利用葡聚糖硫酸钠诱导的炎症性肠病小鼠模型,通过血微核试验和Pig-a基因突变试验评估其全身遗传毒性。

Kirby, Christopher; Baig, Ayesha; Avlasevich, Svetlana L; Torous, Dorothea K; Tian, Shuchang; Singh, Priyanka; Bemis, Jeffrey C; Saubermann, Lawrence J; Dertinger, Stephen D

Assessment of systemic genetic damage in pediatric inflammatory bowel disease

儿童炎症性肠病系统性遗传损伤的评估

Baig, Ayesha; Avlasevich, Svetlana L; Torous, Dorothea K; Bemis, Jeffrey C; Saubermann, Lawrence J; Lovell, David P; MacGregor, James T; Dertinger, Stephen D

Aneugen Molecular Mechanism Assay: Proof-of-Concept With 27 Reference Chemicals

Aneugen分子机制分析:使用27种参考化学品进行概念验证

Bernacki, Derek T; Bryce, Steven M; Bemis, Jeffrey C; Dertinger, Stephen D

Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract

黑升麻提取物诱导微核的非整倍体作用机制的证据

Bernacki, Derek T; Bryce, Steven M; Bemis, Jeffrey C; Dertinger, Stephen D; Witt, Kristine L; Smith-Roe, Stephanie L

3Rs friendly study designs facilitate rat liver and blood micronucleus assays and Pig-a gene mutation assessments: Proof-of-concept with 13 reference chemicals.

3R 友好型研究设计有助于进行大鼠肝脏和血液微核试验以及 Pig-a 基因突变评估:使用 13 种参考化学品进行概念验证

Dertinger Stephen D, Avlasevich Svetlana L, Torous Dorothea K, Singh Priyanka, Khanal Sumee, Kirby Christopher, Drake Amanda, MacGregor James T, Bemis Jeffrey C

Integration of liver and blood micronucleus and Pig-a gene mutation endpoints into rat 28-day repeat-treatment studies: Proof-of-principle with diethylnitrosamine

将肝脏和血液微核以及Pig-a基因突变终点整合到大鼠28天重复治疗研究中:二乙基亚硝胺的概念验证。

Khanal, Sumee; Singh, Priyanka; Avlasevich, Svetlana L; Torous, Dorothea K; Bemis, Jeffrey C; Dertinger, Stephen D

In vivo pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate

体内猪-a 和微核研究原型非整倍体诱导剂长春碱硫酸盐

Avlasevich, Svetlana L; Labash, Carson; Torous, Dorothea K; Bemis, Jeffrey C; MacGregor, James T; Dertinger, Stephen D