日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease

miR155 对阿尔茨海默病中的行为、神经病理学和皮质转录组学的调控

Ben Readhead #, Jean-Vianney Haure-Mirande #, Diego Mastroeni, Mickael Audrain, Tomas Fanutza, Soong H Kim, Robert D Blitzer, Sam Gandy, Joel T Dudley #, Michelle E Ehrlich #

A Novel Approach to Safer Glucocorticoid Receptor-Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition

通过抑制 REDD1(调控发育和 DNA 损伤 1)实现更安全的糖皮质激素受体靶向抗淋巴瘤治疗的新方法

Ekaterina A Lesovaya #, Alena V Savinkova #, Olga V Morozova, Evgeniya S Lylova, Ekaterina M Zhidkova, Evgeny P Kulikov, Kirill I Kirsanov, Anna Klopot, Gleb Baida, Marianna G Yakubovskaya, Leo I Gordon, Ben Readhead, Joel T Dudley, Irina Budunova

PI3K inhibitors protect against glucocorticoid-induced skin atrophy

PI3K 抑制剂可预防糖皮质激素引起的皮肤萎缩

Shivani Agarwal, Salida Mirzoeva, Ben Readhead, Joel T Dudley, Irina Budunova

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden

散发性阿尔茨海默病的综合治疗方法:大脑 Aβ 淀粉样变性小鼠中 TYROBP 缺乏可使临床表型和补体子网络分子病理学正常化,而不会减少 Aβ 负担

Jean-Vianney Haure-Mirande #, Minghui Wang #, Mickael Audrain, Tomas Fanutza, Soong Ho Kim, Szilvia Heja, Ben Readhead, Joel T Dudley, Robert D Blitzer, Eric E Schadt, Bin Zhang #, Sam Gandy #, Michelle E Ehrlich #

Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

临床和基因组数据中的功能丧失变异的综合分析揭示了与心血管特征相关的新基因

Benjamin S Glicksberg, Letizia Amadori, Nicholas K Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M Belbin, Kristin L Ayers, Khader Shameer, Marcus A Badgeley, Kipp W Johnson, Ben Readhead, Bruce J Darrow, Eimear E Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp,

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

对独立的阿尔茨海默病患者群体进行多尺度分析,发现人类疱疹病毒会破坏分子、遗传和临床网络

Ben Readhead, Jean-Vianney Haure-Mirande, Cory C Funk, Matthew A Richards, Paul Shannon, Vahram Haroutunian, Mary Sano, Winnie S Liang, Noam D Beckmann, Nathan D Price, Eric M Reiman, Eric E Schadt, Michelle E Ehrlich, Sam Gandy, Joel T Dudley

Rapamycin Modulates Glucocorticoid Receptor Function, Blocks Atrophogene REDD1, and Protects Skin from Steroid Atrophy

雷帕霉素调节糖皮质激素受体功能,阻断营养基因 REDD1,保护皮肤免受类固醇萎缩

Ekaterina Lesovaya, Shivani Agarwal, Ben Readhead, Elena Vinokour, Gleb Baida, Pankaj Bhalla, Kirill Kirsanov, Marianna Yakubovskaya, Leonidas C Platanias, Joel T Dudley, Irina Budunova

Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain

探索哺乳动物大脑中 eIF2α 失调、急性内质网应激和 DYT1 肌张力障碍之间的相互作用

Genevieve Beauvais, Noela Rodriguez-Losada, Lei Ying, Zuchra Zakirova, Jaime L Watson, Ben Readhead, Paul Gadue, Deborah L French, Michelle E Ehrlich, Pedro Gonzalez-Alegre

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy

删除糖皮质激素受体伴侣 FKBP51 可预防糖皮质激素引起的皮肤萎缩

Gleb Baida, Pankaj Bhalla, Alexander Yemelyanov, Lance A Stechschulte, Weinian Shou, Ben Readhead, Joel T Dudley, Edwin R Sánchez, Irina Budunova

Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions

THAP1/DYT6 突变表明,不同的肌张力障碍基因会破坏相似的神经通路和功能

Zuchra Zakirova, Tomas Fanutza, Justine Bonet, Ben Readhead, Weijia Zhang, Zhengzi Yi, Genevieve Beauvais, Thomas P Zwaka, Laurie J Ozelius, Robert D Blitzer, Pedro Gonzalez-Alegre, Michelle E Ehrlich